Development Level

Tbio 181 | 10,625
Tclin 89 | 602
Tchem 67 | 1,890
Tdark 9 | 7,003

Collection

Eligible Ion Channel Proteins 14 | 117
Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 2 | 145

IMPC Term

preweaning lethality, complete... 19 | 633
abnormal behavior 8 | 226
decreased lean body mass 7 | 195
decreased total body fat amoun... 7 | 186
preweaning lethality, incomple... 7 | 260
decreased bone mineral content 6 | 157
decreased fasted circulating g... 6 | 49
decreased grip strength 6 | 123
embryonic lethality prior to o... 6 | 148
increased lean body mass 6 | 107
abnormal bone structure 5 | 131
decreased circulating alkaline... 5 | 41
decreased prepulse inhibition 5 | 52
hyperactivity 5 | 108
improved glucose tolerance 5 | 56
increased bone mineral content 5 | 92
short tibia 5 | 82
abnormal gait 4 | 51
abnormal retina morphology 4 | 100
decreased body length 4 | 108
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
embryonic lethality prior to t... 4 | 187
enlarged heart 4 | 111
impaired glucose tolerance 4 | 52
increased circulating alkaline... 4 | 119
abnormal epididymis morphology 3 | 31
abnormal heart morphology 3 | 51
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased startle reflex 3 | 48
increased blood urea nitrogen ... 3 | 44
increased circulating chloride... 3 | 43
increased or absent threshold ... 3 | 128
increased startle reflex 3 | 38
prenatal lethality prior to he... 3 | 64
tremors 3 | 34
abnormal behavioral response t... 2 | 52
abnormal heart left ventricle ... 2 | 20
abnormal kidney morphology 2 | 30
abnormal locomotor activation 2 | 26
abnormal retinal pigmentation 2 | 61
abnormal skin morphology 2 | 23
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased hemoglobin content 2 | 53
decreased mean corpuscular hem... 2 | 34
decreased mean platelet volume 2 | 12
decreased pulmonary respirator... 2 | 4
enlarged epididymis 2 | 27
enlarged stomach 2 | 2
impaired righting response 2 | 19
increased circulating creatini... 2 | 29
increased erythrocyte cell num... 2 | 26
increased leukocyte cell numbe... 2 | 37
increased vertical activity 2 | 18
lethargy 2 | 5
limb grasping 2 | 35
male infertility 2 | 62
small thymus 2 | 11
thrombocytopenia 2 | 46
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal lens morphology 1 | 73
abnormal sensory capabilities/... 1 | 3
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased red blood cell distr... 1 | 11
female infertility 1 | 34
hypoactivity 1 | 89
increased circulating bilirubi... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
straub tail 1 | 26
thrombocytosis 1 | 23
trunk curl 1 | 15

Disease

Epilepsy 346 | 346
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Nervous System 343 | 18,561
Digestive Tract 341 | 18,473
Endocrine System 341 | 18,512
Female tissues 341 | 18,647
Urinary Tract 340 | 18,444
Male tissues 339 | 17,969
Liver and Pancreas 338 | 18,136
Skin and soft tissues 337 | 18,115
Cardiovascular System 335 | 17,958
Blood and immune system 331 | 17,995
Respiratory system 326 | 17,484

Target Family

Non-IDG 120 | 11,969
Ion Channel 74 | 341
Enzyme 70 | 4,146
Transporter 26 | 473
GPCR 24 | 408
Transcription Factor 15 | 1,400
Kinase 13 | 634
Epigenetic 3 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synapsin-1 SYN1 Tbio Non-IDG -2.85684 687.9 716
Metabotropic glutamate receptor 4 GRM4 Tchem GPCR -2.32485 207.4 140
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.20483 1368.4 194
CHRNA7-FAM7A fusion protein CHRFAM7A Tbio Non-IDG -1.78124 84.1 71
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.90129 787.3 198
Nitrogen permease regulator 2-like protein NPRL2 Tbio Enzyme -1.25122 21.8 191
Sodium channel protein type 11 subunit alpha SCN11A Tclin Ion Channel -2.44224 238.6 56
28S ribosomal protein S7, mitochondrial MRPS7 Tdark Non-IDG -2.74950 523.2 47
Ethylmalonyl-CoA decarboxylase ECHDC1 Tbio Enzyme -2.14463 126.6 79
Zinc transporter 3 SLC30A3 Tbio Transporter -1.98371 104.9 58