Development Level

Tbio 207 | 11,445
Tdark 43 | 6,588
Tchem 40 | 1,598
Tclin 21 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 24 | 979
embryonic lethality prior to t... 7 | 278
increased total body fat amoun... 7 | 134
preweaning lethality, incomple... 7 | 499
abnormal bone structure 6 | 187
decreased total body fat amoun... 6 | 207
abnormal embryo size 5 | 220
decreased circulating alkaline... 5 | 46
decreased circulating choleste... 5 | 93
embryonic lethality prior to o... 5 | 239
abnormal behavior 4 | 298
decreased circulating HDL chol... 4 | 68
decreased lean body mass 4 | 135
decreased lymphocyte cell numb... 4 | 83
decreased startle reflex 4 | 75
impaired glucose tolerance 4 | 75
increased lean body mass 4 | 172
increased or absent threshold ... 4 | 101
short tibia 4 | 97
abnormal behavioral response t... 3 | 66
abnormal heart morphology 3 | 162
abnormal locomotor behavior 3 | 24
absent startle reflex 3 | 24
decreased body length 3 | 101
decreased body weight 3 | 161
decreased bone mineral density 3 | 126
decreased circulating aspartat... 3 | 34
decreased circulating serum al... 3 | 82
decreased erythrocyte cell num... 3 | 62
decreased exploration in new e... 3 | 11
decreased grip strength 3 | 116
decreased hemoglobin content 3 | 68
decreased vertical activity 3 | 208
enlarged heart 3 | 210
hypoactivity 3 | 132
increased circulating HDL chol... 3 | 80
increased circulating amylase ... 3 | 25
increased circulating choleste... 3 | 66
increased hematocrit 3 | 46
increased red blood cell distr... 3 | 34
small thymus 3 | 16
abnormal bone mineralization 2 | 38
abnormal cornea morphology 2 | 31
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating fructosa... 2 | 30
decreased circulating total pr... 2 | 49
decreased fasted circulating g... 2 | 65
decreased prepulse inhibition 2 | 82
decreased pulmonary respirator... 2 | 5
enlarged stomach 2 | 2
impaired pupillary reflex 2 | 26
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating phosphat... 2 | 26
increased heart weight 2 | 62
increased mean platelet volume 2 | 45
increased spleen weight 2 | 10
increased startle reflex 2 | 112
long tibia 2 | 25
mammalian phenotype 2 | 17
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
absent spleen 1 | 3
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged lymph nodes 1 | 37
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
prenatal lethality 1 | 28
thrombocytosis 1 | 27

Disease

Endometrial cancer 311 | 311
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 296 | 18,159
Female tissues 288 | 17,400
Male tissues 283 | 17,142
Digestive Tract 281 | 17,369
Skin and soft tissues 281 | 17,230
Nervous System 276 | 16,725
Blood and immune system 270 | 16,909
Liver and Pancreas 268 | 16,750
Urinary Tract 268 | 16,678
Respiratory system 267 | 16,393
Cardiovascular System 237 | 15,192

Target Family

Non-IDG 197 | 12,091
Enzyme 31 | 4,145
Kinase 20 | 634
Transcription Factor 20 | 1,400
Ion Channel 18 | 344
Epigenetic 10 | 242
GPCR 6 | 408
Transporter 6 | 473
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Mucin-16 MUC16 Tbio Non-IDG -2.09951 138.4 0
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
VPS10 domain-containing receptor SorCS1 SORCS1 Tbio Non-IDG -1.36030 24.0 81
IgGFc-binding protein FCGBP Tbio Non-IDG -1.31482 19.9 0
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63