Development Level

Tbio 14 | 11,445
Tclin 12 | 613
Tchem 5 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
absent pinna reflex 1 | 23
cleft palate 1 | 8
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Dyspepsia 33 | 33
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 33 | 18,159
Digestive Tract 32 | 17,369
Blood and immune system 29 | 16,909
Female tissues 29 | 17,400
Nervous System 27 | 16,725
Urinary Tract 27 | 16,678
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 17 | 12,091
GPCR 7 | 408
Enzyme 3 | 4,145
Ion Channel 3 | 344
Transporter 3 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Histamine H2 receptor HRH2 Tclin GPCR -3.21267 1595.1 244
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.35296 2270.4 122
Somatostatin SST Tbio Non-IDG -4.14886 13572.0 397
Oncomodulin-1 OCM Tdark Non-IDG -2.22471 170.4 39
Putative oncomodulin-2 OCM2 Tdark Non-IDG -1.99920 96.6 10
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Symplekin SYMPK Tbio Non-IDG -2.60677 393.4 135
Transient receptor potential cation channel subfamily V member 1 TRPV1 Tclin Ion Channel -3.26780 1774.6 373