Development Level

Tbio 431 | 10,625
Tchem 90 | 1,890
Tdark 61 | 7,003
Tclin 20 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible non-olfactory GPCR Proteins 3 | 143
Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 14 | 633
preweaning lethality, incomple... 12 | 260
abnormal behavior 10 | 226
decreased lean body mass 10 | 195
decreased total body fat amoun... 9 | 186
short tibia 7 | 82
abnormal coat/hair pigmentatio... 6 | 54
decreased body length 6 | 108
decreased bone mineral density 6 | 126
embryonic lethality prior to t... 6 | 187
increased circulating alkaline... 6 | 119
abnormal bone structure 5 | 131
abnormal lens morphology 5 | 73
abnormal sleep behavior 5 | 63
decreased grip strength 5 | 123
decreased prepulse inhibition 5 | 52
enlarged heart 5 | 111
hyperactivity 5 | 108
increased bone mineral content 5 | 92
increased lean body mass 5 | 107
abnormal embryo size 4 | 112
abnormal retina morphology 4 | 100
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
decreased circulating HDL chol... 4 | 77
decreased circulating glucose ... 4 | 121
decreased circulating insulin ... 4 | 75
decreased circulating serum al... 4 | 79
decreased heart weight 4 | 44
impaired glucose tolerance 4 | 52
improved glucose tolerance 4 | 56
abnormal eye morphology 3 | 38
abnormal humerus morphology 3 | 11
increased bone mineral density 3 | 52
increased circulating HDL chol... 3 | 63
increased circulating potassiu... 3 | 31
increased fasted circulating g... 3 | 68
increased mean corpuscular hem... 3 | 93
increased vertical activity 3 | 18
abnormal QRS complex 2 | 25
abnormal behavioral response t... 2 | 52
abnormal femur morphology 2 | 14
abnormal neural tube closure 2 | 37
abnormal placenta size 2 | 10
abnormal retinal pigmentation 2 | 61
abnormal rib morphology 2 | 28
abnormal tooth morphology 2 | 24
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased circulating creatini... 2 | 31
decreased circulating free fat... 2 | 39
decreased circulating fructosa... 2 | 31
decreased circulating triglyce... 2 | 83
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 19
decreased threshold for audito... 2 | 32
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
immune system phenotype 2 | 17
increased blood urea nitrogen ... 2 | 44
increased body length 2 | 20
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
increased circulating free fat... 2 | 17
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased mean corpuscular hem... 2 | 25
increased red blood cell distr... 2 | 21
increased respiratory quotient 2 | 12
pallor 2 | 13
prenatal lethality prior to he... 2 | 64
abnormal coping response 1 | 12
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased circulating chloride... 1 | 32
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased red blood cell distr... 1 | 11
dilated heart left ventricle 1 | 10
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased KLRG1+ CD4 alpha bet... 1 | 5
increased circulating alanine ... 1 | 11
increased circulating glucose ... 1 | 16
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

Duchenne muscular dystrophy 602 | 602
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Male tissues 597 | 17,969
Digestive Tract 596 | 18,473
Endocrine System 596 | 18,512
Female tissues 596 | 18,647
Liver and Pancreas 596 | 18,136
Nervous System 596 | 18,561
Urinary Tract 596 | 18,444
Blood and immune system 595 | 17,995
Cardiovascular System 595 | 17,958
Respiratory system 594 | 17,484
Skin and soft tissues 587 | 18,115

Target Family

Non-IDG 410 | 11,971
Enzyme 119 | 4,146
Transcription Factor 20 | 1,400
Kinase 17 | 634
Transporter 17 | 473
GPCR 7 | 406
Ion Channel 7 | 341
Nuclear Receptor 3 | 48
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Endoplasmin HSP90B1 Tchem Non-IDG -2.72785 604.5 748
Protein Smaug homolog 1 SAMD4A Tbio Non-IDG 16.8 58
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
Protein BEX3 BEX3 Tbio Non-IDG -1.87293 81.4 184
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715