Development Level

Tbio 88 | 11,445
Tchem 24 | 1,598
Tclin 7 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 8 | 499
abnormal behavior 4 | 298
abnormal retina morphology 4 | 71
abnormal bone structure 3 | 187
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased body length 3 | 101
decreased bone mineral content 3 | 151
embryonic lethality prior to t... 3 | 278
impaired glucose tolerance 3 | 75
abnormal embryo development 2 | 7
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased grip strength 2 | 116
decreased heart rate 2 | 18
decreased hemoglobin content 2 | 68
decreased red blood cell distr... 2 | 41
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
prenatal lethality 2 | 28
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent adrenal gland 1 | 2
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased kidney weight 1 | 6
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
male infertility 1 | 123
mammalian phenotype 1 | 17
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Dilated ventricles (finding) 121 | 121
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 121 | 18,159
Blood and immune system 119 | 16,909
Digestive Tract 119 | 17,369
Nervous System 119 | 16,725
Female tissues 118 | 17,400
Male tissues 118 | 17,142
Urinary Tract 118 | 16,678
Liver and Pancreas 117 | 16,750
Skin and soft tissues 117 | 17,230
Respiratory system 116 | 16,393
Cardiovascular System 112 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 38 | 4,145
Kinase 12 | 634
Transcription Factor 6 | 1,400
Epigenetic 4 | 242
Transporter 4 | 473
GPCR 2 | 408
Ion Channel 2 | 344
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Vacuolar protein sorting-associated protein 13A VPS13A Tbio Non-IDG -2.19966 172.3 22
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Friend leukemia integration 1 transcription factor FLI1 Tbio Transcription Factor -1.82504 66.8 454
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Solute carrier family 12 member 6 SLC12A6 Tbio Transporter -1.73943 58.4 161
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform PPP2R5D Tbio Enzyme -0.70843 3.59 261
28S ribosomal protein S16, mitochondrial MRPS16 Tbio Non-IDG -0.33244 1.70 61
AMP deaminase 2 AMPD2 Tchem Enzyme -1.74341 53.6 155