Development Level

Tbio 17 | 11,445
Tchem 7 | 1,598
Tclin 7 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytosis 1 | 27

Disease

Diabetes Mellitus, Noninsulin-Dependent 31 | 31
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Skin and soft tissues 29 | 17,230
Liver and Pancreas 28 | 16,750
Urinary Tract 28 | 16,678
Blood and immune system 27 | 16,909
Female tissues 27 | 17,400
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Cardiovascular System 24 | 15,192
Respiratory system 23 | 16,393

Target Family

Enzyme 7 | 4,145
Non-IDG 7 | 12,091
Transcription Factor 6 | 1,400
Kinase 3 | 634
Transporter 3 | 473
GPCR 2 | 408
Nuclear Receptor 2 | 48
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin-like growth factor 2 mRNA-binding protein 2 IGF2BP2 Tbio Non-IDG -1.77792 57.3 400
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Zinc transporter 8 SLC30A8 Tbio Transporter -2.20313 168.0 122
Wolframin WFS1 Tbio Non-IDG -2.40006 260.2 118
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
Melatonin receptor type 1B MTNR1B Tclin GPCR -2.01297 100.6 222
ATP-binding cassette sub-family C member 8 ABCC8 Tclin Transporter -2.92120 869.9 193
Protein phosphatase 1 regulatory subunit 3A PPP1R3A Tbio Enzyme -1.36272 22.6 88
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1 Tchem Enzyme -2.74480 552.8 275
Hepatocyte nuclear factor 1-alpha HNF1A Tbio Transcription Factor -2.87439 680.9 0