Development Level

Tbio 79 | 11,651
Tchem 40 | 1,388
Tclin 21 | 612
Tdark 5 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 9 | 979
increased circulating alkaline... 4 | 122
increased lean body mass 4 | 172
preweaning lethality, incomple... 4 | 499
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
impaired glucose tolerance 3 | 75
increased circulating aspartat... 3 | 15
abnormal behavior 2 | 298
abnormal gait 2 | 69
abnormal locomotor behavior 2 | 24
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating amylase ... 2 | 28
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
increased circulating total pr... 2 | 28
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
small testis 2 | 58
trunk curl 2 | 16
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 81
abnormal lymph node morphology 1 | 3
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal skin condition 1 | 6
cardiovascular system phenotyp... 1 | 36
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
enlarged epididymis 1 | 31
enlarged seminal vesicle 1 | 10
hemorrhage 1 | 23
hyperactivity 1 | 148
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased basophil cell number 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total retina thickne... 1 | 4
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small seminal vesicle 1 | 10
stereotypic behavior 1 | 3
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Diabetes Mellitus, Non-Insulin-Dependent 145 | 145
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 144 | 18,159
Digestive Tract 143 | 17,369
Liver and Pancreas 142 | 16,750
Skin and soft tissues 141 | 17,230
Female tissues 139 | 17,400
Urinary Tract 139 | 16,678
Nervous System 137 | 16,725
Blood and immune system 136 | 16,909
Male tissues 135 | 17,142
Respiratory system 133 | 16,393
Cardiovascular System 129 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 46 | 4,145
Transcription Factor 19 | 1,400
Kinase 8 | 634
Transporter 7 | 473
GPCR 4 | 408
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GNB3 Tbio Non-IDG -2.34836 235.8 161
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.52487 33.2 60
DCC-interacting protein 13-alpha APPL1 Tbio Non-IDG -2.75344 511.0 230
Insulin receptor substrate 2 IRS2 Tbio Non-IDG -2.64133 414.7 227
S-adenosylmethionine synthase isoform type-1 MAT1A Tbio Enzyme -2.11527 125.3 167