Development Level

Tbio 212 | 11,445
Tchem 105 | 1,598
Tclin 90 | 613
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, incomple... 18 | 499
preweaning lethality, complete... 16 | 979
abnormal behavior 15 | 298
decreased total body fat amoun... 14 | 207
decreased body weight 12 | 161
decreased vertical activity 11 | 208
enlarged heart 10 | 210
embryonic lethality prior to t... 8 | 278
hyperactivity 8 | 148
abnormal bone structure 7 | 187
abnormal retina morphology 6 | 71
decreased grip strength 6 | 116
decreased prepulse inhibition 6 | 82
increased lean body mass 6 | 172
abnormal embryo size 5 | 220
decreased body length 5 | 101
decreased circulating HDL chol... 5 | 68
decreased circulating alkaline... 5 | 46
decreased mean corpuscular vol... 5 | 79
increased circulating alkaline... 5 | 122
increased startle reflex 5 | 112
male infertility 5 | 123
prolonged ST segment 5 | 36
abnormal heart morphology 4 | 162
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating insulin ... 4 | 76
decreased hemoglobin content 4 | 68
decreased lean body mass 4 | 135
embryonic lethality prior to o... 4 | 239
hypoactivity 4 | 132
improved glucose tolerance 4 | 79
increased bone mineral content 4 | 108
increased circulating sodium l... 4 | 71
limb grasping 4 | 41
prolonged QT interval 4 | 38
thrombocytopenia 4 | 56
abnormal behavioral response t... 3 | 66
abnormal coat-hair pigmentatio... 3 | 64
abnormal lens morphology 3 | 81
abnormal locomotor behavior 3 | 24
abnormal seminal vesicle morph... 3 | 114
abnormal sleep behavior 3 | 70
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased circulating LDL chol... 3 | 38
decreased circulating alanine ... 3 | 47
decreased circulating fructosa... 3 | 30
decreased circulating potassiu... 3 | 20
decreased fasted circulating g... 3 | 65
decreased mean corpuscular hem... 3 | 50
decreased startle reflex 3 | 75
impaired glucose tolerance 3 | 75
increased circulating chloride... 3 | 41
increased fasted circulating g... 3 | 76
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
tremors 3 | 39
abnormal iris morphology 2 | 13
abnormal kidney morphology 2 | 65
abnormal social-conspecific in... 2 | 3
corneal opacity 2 | 32
decreased basophil cell number 2 | 16
decreased blood urea nitrogen ... 2 | 51
decreased circulating amylase ... 2 | 28
decreased circulating aspartat... 2 | 34
decreased circulating glycerol... 2 | 16
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased heart weight 2 | 27
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
decreased neutrophil cell numb... 2 | 42
decreased pulmonary respirator... 2 | 5
edema 2 | 59
embryonic growth retardation 2 | 106
increased bone mineral density 2 | 72
increased circulating alanine ... 2 | 13
increased circulating amylase ... 2 | 25
increased circulating creatini... 2 | 38
increased exploration in new e... 2 | 8
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
small superior vagus ganglion 2 | 74
small testis 2 | 58
abnormal ear morphology 1 | 9
impaired pupillary reflex 1 | 26
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92

Disease

Depressive disorder 409 | 409
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 399 | 18,159
Digestive Tract 390 | 17,369
Nervous System 390 | 16,725
Female tissues 387 | 17,400
Skin and soft tissues 385 | 17,230
Male tissues 383 | 17,142
Liver and Pancreas 377 | 16,750
Blood and immune system 374 | 16,909
Urinary Tract 369 | 16,678
Respiratory system 367 | 16,393
Cardiovascular System 333 | 15,192

Target Family

Non-IDG 165 | 12,091
Enzyme 106 | 4,145
GPCR 43 | 408
Kinase 24 | 634
Ion Channel 22 | 344
Transcription Factor 19 | 1,400
Transporter 14 | 473
Epigenetic 7 | 242
Nuclear Receptor 7 | 48
TF/Epigenetic 1 | 38
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Trace amine-associated receptor 6 TAAR6 Tbio GPCR -2.06244 115.1 64
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184