Development Level

Tbio 156 | 11,651
Tchem 22 | 1,388
Tclin 15 | 612
Tdark 2 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 25 | 979
decreased body weight 9 | 161
preweaning lethality, incomple... 8 | 499
decreased lean body mass 6 | 135
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
decreased total body fat amoun... 5 | 207
abnormal behavior 4 | 298
decreased bone mineral content 4 | 151
prenatal lethality prior to he... 4 | 87
abnormal embryo size 3 | 220
cataract 3 | 92
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
increased bone mineral density 3 | 72
increased mean corpuscular hem... 3 | 96
male infertility 3 | 123
abnormal coat-hair pigmentatio... 2 | 64
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal snout morphology 2 | 23
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating fructosa... 2 | 30
decreased grip strength 2 | 116
decreased heart rate 2 | 18
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased startle reflex 2 | 112
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cystolithiasis 1 | 3
decreased IgG1 level 1 | 8
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
edema 1 | 59
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
long tibia 1 | 25
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
short tibia 1 | 97
small kidney 1 | 16
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Depressed nasal bridge 195 | 195
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 195 | 18,159
Skin and soft tissues 194 | 17,230
Digestive Tract 193 | 17,369
Nervous System 193 | 16,725
Female tissues 192 | 17,400
Blood and immune system 190 | 16,909
Male tissues 190 | 17,142
Liver and Pancreas 189 | 16,750
Respiratory system 188 | 16,393
Urinary Tract 187 | 16,678
Cardiovascular System 184 | 15,192

Target Family

Non-IDG 79 | 12,091
Enzyme 55 | 4,145
Transcription Factor 27 | 1,400
Kinase 18 | 634
Epigenetic 8 | 242
Ion Channel 3 | 344
Transporter 3 | 473
GPCR 2 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
SET domain-containing protein 5 SETD5 Tbio Epigenetic -0.91515 9.39 43
AMME syndrome candidate gene 1 protein AMMECR1 Tbio Non-IDG -0.63077 4.76 84
Ras-related protein Rab-23 RAB23 Tbio Enzyme -1.63391 45.2 211
T-cell surface protein tactile CD96 Tbio Non-IDG -2.05505 111.7 205
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 Tbio Enzyme -1.43805 32.2 112
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 Tbio Enzyme -2.10120 119.8 88
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.88065 80.4 419
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.21203 161.3 194