Development Level

Tbio 74 | 11,445
Tchem 14 | 1,598
Tclin 7 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to t... 6 | 278
abnormal behavior 4 | 298
decreased body weight 3 | 161
decreased lean body mass 3 | 135
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
increased total body fat amoun... 3 | 134
abnormal embryo size 2 | 220
abnormal stomach morphology 2 | 10
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased startle reflex 2 | 112
limb grasping 2 | 41
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lumbar vertebrae num... 1 | 2
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
short tibia 1 | 97
shortened ST segment 1 | 10

Disease

Decreased size of eyeball 97 | 97
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 95 | 18,159
Male tissues 90 | 17,142
Nervous System 89 | 16,725
Female tissues 88 | 17,400
Skin and soft tissues 88 | 17,230
Digestive Tract 86 | 17,369
Urinary Tract 86 | 16,678
Liver and Pancreas 85 | 16,750
Blood and immune system 83 | 16,909
Respiratory system 83 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 27 | 4,145
Transcription Factor 20 | 1,400
Kinase 6 | 634
Epigenetic 2 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Fanconi anemia group D2 protein FANCD2 Tbio Non-IDG -2.59123 391.6 404
Retinal homeobox protein Rx RAX Tbio Transcription Factor -0.52554 4.68 205
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
D-3-phosphoglycerate dehydrogenase PHGDH Tbio Enzyme -3.17330 1408.2 293