Development Level

Tbio 220 | 11,651
Tchem 38 | 1,388
Tclin 23 | 612
Tdark 15 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 31 | 979
embryonic lethality prior to o... 9 | 239
decreased body weight 8 | 161
decreased lean body mass 7 | 135
embryonic lethality prior to t... 7 | 278
decreased total body fat amoun... 6 | 207
abnormal behavior 5 | 298
decreased bone mineral content 5 | 151
increased total body fat amoun... 5 | 134
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
decreased body length 4 | 101
decreased bone mineral density 4 | 126
decreased vertical activity 4 | 208
male infertility 4 | 123
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating fructosa... 3 | 30
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased startle reflex 3 | 75
enlarged heart 3 | 210
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased mean corpuscular hem... 3 | 96
prenatal lethality prior to he... 3 | 87
small kidney 3 | 16
abnormal coat-hair pigmentatio... 2 | 64
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
abnormal snout morphology 2 | 23
abnormal startle reflex 2 | 15
abnormal tail morphology 2 | 25
cataract 2 | 92
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating amylase ... 2 | 28
decreased circulating choleste... 2 | 93
decreased grip strength 2 | 116
decreased heart weight 2 | 27
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
enlarged spleen 2 | 41
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased lean body mass 2 | 172
prenatal lethality 2 | 28
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
decreased IgE level 1 | 6
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased exploration in new e... 1 | 11
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased anti-nuclear antigen... 1 | 19
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased body weight 1 | 25
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating lipase l... 1 | 3
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased startle reflex 1 | 112
limb grasping 1 | 41
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Cryptorchidism 296 | 296
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 292 | 18,159
Female tissues 282 | 17,400
Digestive Tract 281 | 17,369
Male tissues 280 | 17,142
Skin and soft tissues 279 | 17,230
Blood and immune system 277 | 16,909
Nervous System 275 | 16,725
Respiratory system 273 | 16,393
Urinary Tract 271 | 16,678
Liver and Pancreas 270 | 16,750
Cardiovascular System 254 | 15,192

Target Family

Non-IDG 144 | 12,091
Enzyme 67 | 4,145
Transcription Factor 39 | 1,400
Kinase 17 | 634
Epigenetic 12 | 242
GPCR 9 | 408
Nuclear Receptor 3 | 48
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.51747 3.15 91
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Homeobox protein SIX6 SIX6 Tbio Transcription Factor -2.23077 163.2 112
SET domain-containing protein 5 SETD5 Tbio Epigenetic -0.91515 9.39 43
Deleted in azoospermia protein 1 DAZ1 Tbio Non-IDG -2.24914 176.6 159
Ankyrin repeat and LEM domain-containing protein 2 ANKLE2 Tbio Non-IDG -1.07238 11.8 76
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Ras-related protein Rab-23 RAB23 Tbio Enzyme -1.63391 45.2 211
Insulin-like peptide INSL5 INSL5 Tbio Non-IDG -1.42311 26.9 46