Development Level

Tbio 194 | 10,625
Tchem 56 | 1,890
Tdark 35 | 7,003
Tclin 19 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
decreased lean body mass 5 | 195
increased circulating HDL chol... 5 | 63
abnormal bone structure 4 | 131
abnormal lens morphology 4 | 73
increased circulating choleste... 4 | 53
increased mean corpuscular hem... 4 | 93
preweaning lethality, incomple... 4 | 260
abnormal tooth morphology 3 | 24
decreased CD4-positive, CD25-p... 3 | 24
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased effector memory CD8-... 3 | 24
decreased neutrophil cell numb... 3 | 37
decreased rib number 3 | 59
embryonic lethality prior to t... 3 | 187
increased circulating serum al... 3 | 25
increased hemoglobin content 3 | 45
increased leukocyte cell numbe... 3 | 37
increased neutrophil cell numb... 3 | 15
abnormal behavior 2 | 226
abnormal cornea morphology 2 | 24
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal eye morphology 2 | 38
abnormal retina morphology 2 | 100
abnormal rib morphology 2 | 28
abnormal skin morphology 2 | 23
decreased B cell number 2 | 30
decreased T cell number 2 | 31
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating creatini... 2 | 31
decreased circulating triglyce... 2 | 83
decreased gamma-delta T cell n... 2 | 18
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
decreased lumbar vertebrae num... 2 | 62
decreased lymphocyte cell numb... 2 | 9
decreased mature B cell number 2 | 25
decreased mean corpuscular hem... 2 | 19
embryonic lethality prior to o... 2 | 148
enlarged epididymis 2 | 27
increased circulating alkaline... 2 | 119
increased circulating free fat... 2 | 17
increased circulating triglyce... 2 | 24
increased effector memory CD4-... 2 | 15
increased effector memory CD8-... 2 | 14
increased grip strength 2 | 83
increased monocyte cell number 2 | 27
increased rib number 2 | 41
vertebral fusion 2 | 23
abnormal QRS complex 1 | 25
abnormal cranium morphology 1 | 32
abnormal eye size 1 | 11
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
cataract 1 | 26
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased Ly6C low monocyte nu... 1 | 23
decreased alpha-beta T cell nu... 1 | 12
decreased basophil cell number 1 | 11
decreased circulating bilirubi... 1 | 14
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased monocyte cell number 1 | 28
decreased thoracic vertebrae n... 1 | 7
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hydrops fetalis 1 | 22
increased CD4-positive, CD25-p... 1 | 18
increased KLRG1+ CD4 alpha bet... 1 | 5
increased NK cell number 1 | 19
increased body length 1 | 20
increased body weight 1 | 42
increased caudal vertebrae num... 1 | 8
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
microphthalmia 1 | 15
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
small superior vagus ganglion 1 | 20

Disease

Crohn's disease 304 | 304
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 301 | 18,473
Nervous System 301 | 18,561
Urinary Tract 301 | 18,444
Female tissues 300 | 18,647
Liver and Pancreas 300 | 18,136
Skin and soft tissues 300 | 18,115
Cardiovascular System 299 | 17,958
Endocrine System 299 | 18,512
Blood and immune system 298 | 17,995
Male tissues 293 | 17,969
Respiratory system 293 | 17,484

Target Family

Non-IDG 171 | 11,971
Enzyme 60 | 4,146
Transcription Factor 26 | 1,400
Kinase 13 | 634
Transporter 12 | 473
Epigenetic 8 | 242
GPCR 8 | 406
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
Coagulation factor XI F11 Tchem Enzyme -2.65863 487.3 216
Hermansky-Pudlak syndrome 5 protein HPS5 Tbio Non-IDG -1.13658 13.9 71
Transmembrane protein 258 TMEM258 Tdark Non-IDG 0.12 1.54 5
Myeloblastin PRTN3 Tchem Enzyme -3.41745 2809.9 300
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305
Phosphatase and actin regulator 2 PHACTR2 Tbio Enzyme -0.48667 0.00000 71
Galactoside 2-alpha-L-fucosyltransferase 2 FUT2 Tbio Enzyme -3.02835 1070.9 91