Development Level

Tbio 230 | 11,651
Tchem 42 | 1,388
Tdark 29 | 6,593
Tclin 20 | 612

Collection

GPCR: IDG Consortium (Complete... 3 | 25
Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, incomple... 13 | 499
preweaning lethality, complete... 11 | 979
abnormal behavior 7 | 298
decreased vertical activity 6 | 208
abnormal bone structure 5 | 187
increased startle reflex 5 | 112
decreased bone mineral content 4 | 151
embryonic lethality prior to t... 4 | 278
hypoactivity 4 | 132
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
abnormal tooth morphology 3 | 24
cataract 3 | 92
decreased body weight 3 | 161
decreased bone mineral density 3 | 126
decreased circulating triglyce... 3 | 79
decreased lean body mass 3 | 135
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 96
abnormal cornea morphology 2 | 31
abnormal cranium morphology 2 | 36
abnormal epididymis morphology 2 | 42
abnormal eye anterior chamber ... 2 | 9
abnormal eye morphology 2 | 68
abnormal lens morphology 2 | 81
abnormal locomotor behavior 2 | 24
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
absent startle reflex 2 | 24
decreased CD8-positive, alpha-... 2 | 8
decreased T cell number 2 | 15
decreased basophil cell number 2 | 16
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased large unstained cell... 2 | 11
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
edema 2 | 59
enlarged epididymis 2 | 31
enlarged lymph nodes 2 | 37
increased B cell number 2 | 9
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating calcium ... 2 | 34
increased circulating free fat... 2 | 20
increased circulating serum al... 2 | 22
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased lean body mass 2 | 172
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent spleen 1 | 3
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating creatine... 1 | 4
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged urinary bladder 1 | 8
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased monocyte cell number 1 | 63
persistence of hyaloid vascula... 1 | 33
small kidney 1 | 16
small testis 1 | 58
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Crohn's disease 321 | 321
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 312 | 18,159
Digestive Tract 308 | 17,369
Female tissues 307 | 17,400
Skin and soft tissues 305 | 17,230
Blood and immune system 303 | 16,909
Male tissues 301 | 17,142
Urinary Tract 301 | 16,678
Liver and Pancreas 300 | 16,750
Nervous System 296 | 16,725
Respiratory system 296 | 16,393
Cardiovascular System 270 | 15,192

Target Family

Non-IDG 180 | 12,091
Enzyme 66 | 4,145
Transcription Factor 29 | 1,400
Kinase 14 | 634
Transporter 10 | 473
Epigenetic 8 | 242
GPCR 8 | 408
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Proteasome assembly chaperone 1 PSMG1 Tbio Non-IDG -0.90381 8.14 122
Proton-coupled amino acid transporter 4 SLC36A4 Tbio Transporter -1.46987 30.6 45
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
Intelectin-1 ITLN1 Tbio Non-IDG -2.49500 337.0 194
Integrin beta-7 ITGB7 Tclin Non-IDG -1.63572 38.4 374
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.91291 722.8 693
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.71721 536.2 438
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.82293 59.0 314