Development Level

Tbio 54 | 11,445
Tchem 12 | 1,598
Tclin 7 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 4 | 278
abnormal cornea morphology 3 | 31
embryonic lethality prior to o... 3 | 239
impaired pupillary reflex 3 | 26
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
embryonic growth retardation 2 | 106
increased heart rate variabili... 2 | 7
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal placement of pupils 1 | 6
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
cardiovascular system phenotyp... 1 | 36
decreased NK T cell number 1 | 2
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
iris synechia 1 | 3
limb grasping 1 | 41
long tail 1 | 1
long tibia 1 | 25
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
thick tail 1 | 1
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Craniosynostosis 74 | 74
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 74 | 18,159
Female tissues 74 | 17,400
Liver and Pancreas 74 | 16,750
Skin and soft tissues 74 | 17,230
Digestive Tract 73 | 17,369
Blood and immune system 72 | 16,909
Male tissues 72 | 17,142
Nervous System 72 | 16,725
Respiratory system 72 | 16,393
Urinary Tract 70 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 14 | 4,145
Transcription Factor 10 | 1,400
Kinase 9 | 634
Epigenetic 3 | 242
Ion Channel 2 | 344
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
ETS domain-containing transcription factor ERF ERF Tbio Transcription Factor -2.42588 268.8 257
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Ephrin-A4 EFNA4 Tbio Non-IDG -1.23647 17.4 213
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23896 18.1 117