Development Level

Tbio 23 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal heart morphology 2 | 162
decreased circulating insulin ... 2 | 76
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal maxilla morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
enlarged spleen 1 | 41
hydrometra 1 | 53
male infertility 1 | 123
premature death 1 | 5

Disease

Congenital ichthyosiform erythroderma 28 | 28
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 28 | 17,369
Female tissues 28 | 17,400
Skin and soft tissues 28 | 17,230
Blood and immune system 27 | 16,909
Endocrine System 26 | 18,159
Male tissues 26 | 17,142
Urinary Tract 23 | 16,678
Nervous System 22 | 16,725
Liver and Pancreas 21 | 16,750
Respiratory system 18 | 16,393
Cardiovascular System 13 | 15,192

Target Family

Enzyme 15 | 4,145
Non-IDG 10 | 12,091
Transporter 2 | 473
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
Caspase-14 CASP14 Tchem Enzyme -1.81937 73.7 348
Ceramide synthase 3 CERS3 Tbio Transcription Factor -1.06194 11.5 105
Magnesium transporter NIPA4 NIPAL4 Tbio Non-IDG -1.20246 15.0 58
Lathosterol oxidase SC5D Tbio Enzyme -1.42233 28.3 26
Keratin, type II cytoskeletal 2 epidermal KRT2 Tbio Non-IDG -1.64971 43.0 144
Lipase member N LIPN Tbio Enzyme -2.72363 506.8 64
Keratin, type I cytoskeletal 10 KRT10 Tbio Non-IDG -2.84299 654.9 785
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -2.03967 107.1 42