Development Level

Tbio 69 | 11,445
Tchem 13 | 1,598
Tclin 10 | 613
Tdark 9 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal heart morphology 5 | 162
enlarged heart 4 | 210
decreased lymphocyte cell numb... 3 | 83
increased monocyte cell number 3 | 63
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal eye anterior chamber ... 2 | 9
abnormal eye morphology 2 | 68
abnormal seminal vesicle morph... 2 | 114
decreased prepulse inhibition 2 | 82
decreased thermal nociceptive ... 2 | 2
decreased total body fat amoun... 2 | 207
edema 2 | 59
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal duodenum morphology 1 | 4
abnormal hindbrain morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
eye hemorrhage 1 | 1
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123
short tibia 1 | 97
small heart 1 | 10

Disease

Common variable immunodeficiency 101 | 101
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 99 | 16,909
Digestive Tract 99 | 17,369
Endocrine System 99 | 18,159
Female tissues 99 | 17,400
Liver and Pancreas 99 | 16,750
Male tissues 99 | 17,142
Urinary Tract 99 | 16,678
Respiratory system 98 | 16,393
Skin and soft tissues 98 | 17,230
Cardiovascular System 93 | 15,192
Nervous System 91 | 16,725

Target Family

Non-IDG 62 | 12,091
Enzyme 18 | 4,145
Transcription Factor 12 | 1,400
GPCR 4 | 408
Kinase 4 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194
Insulin, isoform 2 INS-IGF2 Tbio Non-IDG -0.94621 7.72 72
Endoplasmic reticulum aminopeptidase 2 ERAP2 Tchem Enzyme -1.73764 53.1 76
Immunoglobulin J chain JCHAIN Tbio Non-IDG -2.58576 355.8 218
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184