1. Home
  2. Targets
Target Filters...

Development Level

Tbio 25 | 11,445
Tclin 24 | 613
Tchem 15 | 1,598
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

decreased vertical activity 3 | 208
preweaning lethality, incomple... 3 | 499
abnormal behavioral response t... 2 | 66
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
convulsive seizures 1 | 13
decreased circulating aspartat... 1 | 34
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged cecum 1 | 5
enlarged uterus 1 | 11
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating creatine... 1 | 5
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
prolonged ST segment 1 | 36
short tibia 1 | 97
small heart 1 | 10
small superior vagus ganglion 1 | 74

Disease

Common cold 67 | 67
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 67 | 17,369
Female tissues 65 | 17,400
Liver and Pancreas 65 | 16,750
Skin and soft tissues 65 | 17,230
Blood and immune system 64 | 16,909
Endocrine System 64 | 18,159
Respiratory system 64 | 16,393
Urinary Tract 63 | 16,678
Male tissues 61 | 17,142
Nervous System 59 | 16,725
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 33 | 12,091
GPCR 19 | 408
Enzyme 11 | 4,145
Ion Channel 2 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 222 ZNF222 Tdark Transcription Factor 0.03 0.50 55
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
Lysosomal Pro-X carboxypeptidase PRCP Tchem Enzyme -1.87633 85.9 165
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RHNO1 Tbio Non-IDG -3.20363 1560.8 3
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
Mucin-5AC MUC5AC Tbio Non-IDG -3.22130 1630.6 458
Taste receptor type 2 member 4 TAS2R4 Tbio GPCR -1.29219 17.6 27
Taste receptor type 2 member 14 TAS2R14 Tbio GPCR -1.18570 15.5 48
Cadherin-related family member 3 CDHR3 Tdark Non-IDG -1.12856 13.9 46