1. Home
  2. Targets
Target Filters...

Development Level

Tbio 25 | 11,445
Tclin 24 | 613
Tchem 15 | 1,598
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

decreased vertical activity 3 | 208
preweaning lethality, incomple... 3 | 499
abnormal behavioral response t... 2 | 66
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
convulsive seizures 1 | 13
decreased circulating aspartat... 1 | 34
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged cecum 1 | 5
enlarged uterus 1 | 11
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating creatine... 1 | 5
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
prolonged ST segment 1 | 36
short tibia 1 | 97
small heart 1 | 10
small superior vagus ganglion 1 | 74

Disease

Common cold 67 | 67
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 67 | 17,369
Female tissues 65 | 17,400
Liver and Pancreas 65 | 16,750
Skin and soft tissues 65 | 17,230
Blood and immune system 64 | 16,909
Endocrine System 64 | 18,159
Respiratory system 64 | 16,393
Urinary Tract 63 | 16,678
Male tissues 61 | 17,142
Nervous System 59 | 16,725
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 33 | 12,091
GPCR 19 | 408
Enzyme 11 | 4,145
Ion Channel 2 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RHNO1 Tbio Non-IDG -3.20363 1560.8 3
Lysosomal Pro-X carboxypeptidase PRCP Tchem Enzyme -1.87633 85.9 165
Cadherin-related family member 3 CDHR3 Tdark Non-IDG -1.12856 13.9 46
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
Taste receptor type 2 member 14 TAS2R14 Tbio GPCR -1.18570 15.5 48
Taste receptor type 2 member 4 TAS2R4 Tbio GPCR -1.29219 17.6 27
Zinc finger protein 222 ZNF222 Tdark Transcription Factor 0.03 0.50 55
Muscarinic acetylcholine receptor M1 CHRM1 Tclin GPCR -2.16159 140.8 222