Development Level

Tbio 45 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased circulating alkaline... 4 | 122
decreased circulating glucose ... 3 | 126
embryonic lethality prior to t... 3 | 278
abnormal QT variability 2 | 10
abnormal behavior 2 | 298
abnormal craniofacial morpholo... 2 | 33
abnormal embryo size 2 | 220
abnormal neural tube closure 2 | 46
abnormal vibrissa morphology 2 | 25
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased lean body mass 2 | 135
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
prolonged PR interval 2 | 15
abnormal embryo turning 1 | 31
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal placenta size 1 | 20
abnormal tail bud morphology 1 | 8
decreased body length 1 | 101
decreased cardiac stroke volum... 1 | 6
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased lumbar vertebrae num... 1 | 2
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
impaired glucose tolerance 1 | 75
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
long tibia 1 | 25
pallor 1 | 34
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 74

Disease

Coloboma 51 | 51
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 51 | 18,159
Male tissues 47 | 17,142
Digestive Tract 45 | 17,369
Female tissues 45 | 17,400
Urinary Tract 44 | 16,678
Nervous System 43 | 16,725
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Liver and Pancreas 42 | 16,750
Respiratory system 41 | 16,393
Cardiovascular System 38 | 15,192

Target Family

Non-IDG 25 | 12,091
Transcription Factor 17 | 1,400
Enzyme 5 | 4,145
Epigenetic 2 | 242
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sal-like protein 4 SALL4 Tbio Transcription Factor -2.64737 454.3 165
DBF4-type zinc finger-containing protein 2 ZDBF2 Tbio Non-IDG -0.82246 7.11 9
Protein C10 C12orf57 Tbio Non-IDG -2.17919 144.7 27
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Forkhead box protein E3 FOXE3 Tbio Transcription Factor -1.53701 31.5 150
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157