Development Level

Tbio 29 | 10,625
Tclin 29 | 602
Tchem 25 | 1,890
Tdark 5 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

abnormal behavior 5 | 226
preweaning lethality, incomple... 4 | 260
abnormal behavioral response t... 3 | 52
preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
decreased prepulse inhibition 2 | 52
hyperactivity 2 | 108
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 107
increased rib number 2 | 41
increased vertical activity 2 | 18
male infertility 2 | 62
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal spinal cord morpholog... 1 | 8
abnormal tooth morphology 1 | 24
absent seminal vesicle 1 | 2
absent teeth 1 | 4
cardiovascular system phenotyp... 1 | 35
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased cardiac muscle contr... 1 | 5
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased pulmonary respirator... 1 | 4
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged spleen 1 | 26
female infertility 1 | 34
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased circulating alanine ... 1 | 11
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased grip strength 1 | 83
limb grasping 1 | 35
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

Cocaine-Related Disorders 88 | 88
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Endocrine System 88 | 18,512
Female tissues 88 | 18,647
Nervous System 88 | 18,561
Urinary Tract 87 | 18,444
Digestive Tract 86 | 18,473
Skin and soft tissues 86 | 18,115
Cardiovascular System 85 | 17,958
Liver and Pancreas 85 | 18,136
Male tissues 84 | 17,969
Respiratory system 84 | 17,484
Blood and immune system 83 | 17,995

Target Family

Non-IDG 33 | 11,971
GPCR 18 | 406
Kinase 9 | 634
Enzyme 8 | 4,146
Transcription Factor 6 | 1,400
Ion Channel 5 | 341
Transporter 4 | 473
Epigenetic 3 | 242
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.76384 47.5 542
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.32467 28.6 99