Development Level

Tbio 77 | 11,651
Tchem 15 | 1,388
Tclin 14 | 612
Tdark 2 | 6,593

IMPC Phenotype

decreased total body fat amoun... 4 | 207
increased circulating alkaline... 4 | 122
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
preweaning lethality, complete... 3 | 979
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased exploration in new e... 2 | 11
decreased heart rate 2 | 18
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
hypoactivity 2 | 132
increased body length 2 | 32
increased heart weight 2 | 62
increased startle reflex 2 | 112
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
absent adrenal gland 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased urine creatinine lev... 1 | 3
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
premature death 1 | 5
prenatal lethality 1 | 28
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Coarse facial features 108 | 108
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 106 | 18,159
Nervous System 106 | 16,725
Female tissues 104 | 17,400
Skin and soft tissues 104 | 17,230
Blood and immune system 103 | 16,909
Digestive Tract 103 | 17,369
Liver and Pancreas 103 | 16,750
Urinary Tract 103 | 16,678
Male tissues 101 | 17,142
Respiratory system 100 | 16,393
Cardiovascular System 99 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 34 | 4,145
Transcription Factor 14 | 1,400
Transporter 7 | 473
Kinase 6 | 634
Epigenetic 4 | 242
Ion Channel 3 | 344
GPCR 2 | 408
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual oxidase 2 DUOX2 Tbio Enzyme -2.45061 251.8 126
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
AP-4 complex subunit sigma-1 AP4S1 Tdark Non-IDG -0.68049 4.42 25
Thrombopoietin receptor MPL Tclin Non-IDG -2.74303 582.0 186
AP-4 complex subunit beta-1 AP4B1 Tbio Non-IDG -0.79214 6.23 124
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168
RNA-binding motif protein, X chromosome RBMX Tbio Non-IDG -1.52402 35.8 98