Development Level

Tbio 211 | 11,445
Tchem 33 | 1,598
Tclin 15 | 613
Tdark 12 | 6,588

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 38 | 979
abnormal embryo size 9 | 220
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 7 | 239
preweaning lethality, incomple... 7 | 499
decreased circulating glucose ... 6 | 126
decreased lean body mass 6 | 135
increased circulating alkaline... 6 | 122
abnormal behavior 5 | 298
abnormal gait 5 | 69
decreased body weight 5 | 161
enlarged heart 5 | 210
prenatal lethality prior to he... 5 | 87
abnormal heart morphology 4 | 162
decreased vertical activity 4 | 208
enlarged lymph nodes 4 | 37
hyperactivity 4 | 148
increased or absent threshold ... 4 | 101
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
abnormal body wall morphology 3 | 9
abnormal facial morphology 3 | 17
abnormal neural tube closure 3 | 46
abnormal seminal vesicle morph... 3 | 114
cataract 3 | 92
cleft palate 3 | 8
decreased blood urea nitrogen ... 3 | 51
decreased body length 3 | 101
decreased startle reflex 3 | 75
edema 3 | 59
hypoactivity 3 | 132
increased body weight 3 | 25
prolonged QT interval 3 | 38
small superior vagus ganglion 3 | 74
abnormal eye morphology 2 | 68
abnormal head shape 2 | 10
abnormal joint morphology 2 | 23
abnormal lens morphology 2 | 81
abnormal limb morphology 2 | 13
abnormal locomotor behavior 2 | 24
abnormal placenta size 2 | 20
abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
abnormal tail morphology 2 | 25
abnormal testis morphology 2 | 43
absent startle reflex 2 | 24
decreased bone mineral content 2 | 151
decreased circulating aspartat... 2 | 34
decreased circulating bilirubi... 2 | 19
decreased circulating choleste... 2 | 93
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased spleen weight 2 | 10
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hydrometra 2 | 53
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating calcium ... 2 | 34
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
limb grasping 2 | 41
microphthalmia 2 | 26
pale yolk sac 2 | 25
pallor 2 | 34
protruding tongue 2 | 3
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
iris synechia 1 | 3
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
vertebral fusion 1 | 23

Disease

Cleft Palate 271 | 271
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 267 | 18,159
Digestive Tract 260 | 17,369
Male tissues 260 | 17,142
Female tissues 259 | 17,400
Skin and soft tissues 259 | 17,230
Nervous System 253 | 16,725
Liver and Pancreas 251 | 16,750
Blood and immune system 250 | 16,909
Urinary Tract 250 | 16,678
Respiratory system 242 | 16,393
Cardiovascular System 234 | 15,192

Target Family

Non-IDG 133 | 12,091
Transcription Factor 55 | 1,400
Enzyme 50 | 4,145
Kinase 15 | 634
Ion Channel 5 | 344
Epigenetic 4 | 242
Transporter 4 | 473
GPCR 2 | 408
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spermine synthase SMS Tchem Enzyme -1.50353 28.6 215
Cryptic protein CFC1 Tbio Non-IDG -1.89131 76.4 159
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
WASH complex subunit 5 WASHC5 Tbio Non-IDG -1.43182 26.4 38
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Dimethylglycine dehydrogenase, mitochondrial DMGDH Tbio Enzyme -1.39556 25.3 115