Development Level

Tbio 116 | 11,445
Tchem 26 | 1,598
Tdark 25 | 6,588
Tclin 17 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 5 | 499
decreased body weight 4 | 161
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased circulating aspartat... 3 | 34
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased startle reflex 3 | 112
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal vibrissa morphology 2 | 25
anophthalmia 2 | 33
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased exploration in new e... 2 | 11
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
decreased startle reflex 2 | 75
decreased total retina thickne... 2 | 17
enlarged spleen 2 | 41
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating magnesiu... 2 | 10
increased heart weight 2 | 62
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal esophagus morphology 1 | 5
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged uterus 1 | 11
female infertility 1 | 60
impaired pupillary reflex 1 | 26
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
irregularly shaped pupil 1 | 7
male infertility 1 | 123
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
short tibia 1 | 97
small epididymis 1 | 3
small liver 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Chronic obstructive pulmonary disease 184 | 184
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 176 | 18,159
Female tissues 173 | 17,400
Skin and soft tissues 173 | 17,230
Digestive Tract 172 | 17,369
Nervous System 171 | 16,725
Liver and Pancreas 170 | 16,750
Male tissues 169 | 17,142
Blood and immune system 168 | 16,909
Urinary Tract 165 | 16,678
Respiratory system 164 | 16,393
Cardiovascular System 156 | 15,192

Target Family

Non-IDG 103 | 12,091
Enzyme 43 | 4,145
Transcription Factor 9 | 1,400
Ion Channel 8 | 344
Epigenetic 6 | 242
GPCR 6 | 408
Kinase 4 | 634
Nuclear Receptor 2 | 48
oGPCR 2 | 421
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
NACHT and WD repeat domain-containing protein 2 NWD2 Tdark Non-IDG -0.79588 6.31 2
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Testis-specific Y-encoded-like protein 4 TSPYL4 Tdark Non-IDG -0.11115 0.87 119
Probable RNA-binding protein 19 RBM19 Tbio Non-IDG -0.42051 3.55 37
Zinc finger protein with KRAB and SCAN domains 3 ZKSCAN3 Tbio Transcription Factor -0.90118 10.2 101
Secreted and transmembrane protein 1 SECTM1 Tbio Non-IDG -0.82741 7.99 65
CMT1A duplicated region transcript 4 protein CDRT4 Tdark Non-IDG 0.00000 0
Coiled-coil domain-containing protein 38 CCDC38 Tdark Non-IDG -0.33995 2.17 125
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177