Development Level

Tbio 157 | 10,625
Tchem 45 | 1,890
Tdark 24 | 7,003
Tclin 16 | 602

Collection

Eligible Kinase Proteins 4 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
preweaning lethality, incomple... 6 | 260
increased mean corpuscular vol... 4 | 91
abnormal lens morphology 3 | 73
abnormal retina morphology 3 | 100
abnormal tooth morphology 3 | 24
decreased erythrocyte cell num... 3 | 43
decreased hemoglobin content 3 | 53
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
increased lean body mass 3 | 107
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
abnormal spleen morphology 2 | 36
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
enlarged spleen 2 | 26
increased circulating alkaline... 2 | 119
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
increased or absent threshold ... 2 | 128
increased prepulse inhibition 2 | 21
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased fasted circulating g... 1 | 49
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased red blood cell distr... 1 | 11
decreased respiratory quotient 1 | 12
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
enlarged adrenal glands 1 | 3
female infertility 1 | 34
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased erythrocyte cell num... 1 | 26
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
increased spleen weight 1 | 3
male infertility 1 | 62
oligodactyly 1 | 14
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
prolonged PR interval 1 | 4
shortened RR interval 1 | 19
small superior vagus ganglion 1 | 20
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

Chronic Lymphocytic Leukemia 242 | 242
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 241 | 18,473
Liver and Pancreas 241 | 18,136
Nervous System 241 | 18,561
Blood and immune system 240 | 17,995
Endocrine System 240 | 18,512
Female tissues 240 | 18,647
Urinary Tract 240 | 18,444
Cardiovascular System 239 | 17,958
Male tissues 239 | 17,969
Skin and soft tissues 239 | 18,115
Respiratory system 238 | 17,484

Target Family

Non-IDG 125 | 11,971
Enzyme 55 | 4,146
Transcription Factor 22 | 1,400
Kinase 21 | 634
Ion Channel 5 | 341
Transporter 4 | 473
Epigenetic 3 | 242
GPCR 3 | 406
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Replication factor C subunit 5 RFC5 Tbio Non-IDG -1.02728 11.1 64
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 HACD1 Tbio Enzyme -1.46870 28.7 59
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.40375 25.5 174
RCC1 and BTB domain-containing protein 1 RCBTB1 Tbio Non-IDG -1.74139 45.5 174