Development Level

Tbio 185 | 11,445
Tchem 39 | 1,598
Tclin 20 | 613
Tdark 18 | 6,588

Collection

Kinase: IDG Consortium (Target... 4 | 125
RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 11 | 499
abnormal lens morphology 5 | 81
cataract 5 | 92
decreased lymphocyte cell numb... 5 | 83
increased lean body mass 5 | 172
abnormal embryo size 4 | 220
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
increased total body fat amoun... 4 | 134
abnormal behavior 3 | 298
abnormal gait 3 | 69
abnormal heart morphology 3 | 162
abnormal skin morphology 3 | 50
abnormal tooth morphology 3 | 24
decreased circulating choleste... 3 | 93
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
short tibia 3 | 97
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal retina morphology 2 | 71
abnormal snout morphology 2 | 23
abnormal spleen morphology 2 | 55
decreased caudal vertebrae num... 2 | 53
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased large unstained cell... 2 | 11
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased hematocrit 2 | 46
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
increased spleen weight 2 | 10
increased startle reflex 2 | 112
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal vitreous body morphol... 1 | 10
anophthalmia 1 | 33
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged epididymis 1 | 31
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
shortened RR interval 1 | 17

Disease

Chronic Lymphocytic Leukemia 262 | 262
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 258 | 16,909
Digestive Tract 257 | 17,369
Endocrine System 257 | 18,159
Female tissues 257 | 17,400
Skin and soft tissues 257 | 17,230
Liver and Pancreas 255 | 16,750
Male tissues 255 | 17,142
Respiratory system 255 | 16,393
Urinary Tract 255 | 16,678
Nervous System 253 | 16,725
Cardiovascular System 252 | 15,192

Target Family

Non-IDG 134 | 12,091
Enzyme 60 | 4,145
Kinase 25 | 634
Transcription Factor 23 | 1,400
Ion Channel 5 | 344
Transporter 5 | 473
GPCR 4 | 408
Epigenetic 3 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Disintegrin and metalloproteinase domain-containing protein 29 ADAM29 Tbio Enzyme -1.11051 12.4 58
Uridine-cytidine kinase-like 1 UCKL1 Tdark Kinase -0.15970 2.21 110
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
E3 ubiquitin-protein ligase RNF130 RNF130 Tbio Enzyme -2.20315 148.8 86