Development Level

Tbio 107 | 11,651
Tchem 33 | 1,388
Tclin 9 | 612
Tdark 6 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
decreased mean corpuscular vol... 5 | 79
increased startle reflex 4 | 112
preweaning lethality, complete... 4 | 979
abnormal heart morphology 3 | 162
abnormal kidney morphology 3 | 65
enlarged heart 3 | 210
increased circulating HDL chol... 3 | 80
increased mean corpuscular vol... 3 | 92
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating creatini... 2 | 39
decreased circulating serum al... 2 | 82
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
female infertility 2 | 60
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased mean corpuscular hem... 2 | 96
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
short tibia 2 | 97
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal lymph node morphology 1 | 3
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal thoracic cage shape 1 | 3
abnormal vibrissa morphology 1 | 25
absent seminal vesicle 1 | 4
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased respiratory quotient 1 | 16
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased body weight 1 | 25
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
shortened QRS complex duration 1 | 1
small superior vagus ganglion 1 | 74
small uterus 1 | 3
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Cholestasis 155 | 155
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Liver and Pancreas 153 | 16,750
Digestive Tract 151 | 17,369
Endocrine System 151 | 18,159
Urinary Tract 148 | 16,678
Skin and soft tissues 146 | 17,230
Male tissues 145 | 17,142
Female tissues 144 | 17,400
Blood and immune system 137 | 16,909
Nervous System 134 | 16,725
Respiratory system 133 | 16,393
Cardiovascular System 120 | 15,192

Target Family

Non-IDG 73 | 12,091
Enzyme 38 | 4,145
Transporter 24 | 473
Transcription Factor 8 | 1,400
Nuclear Receptor 6 | 48
Kinase 4 | 634
GPCR 2 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075