Development Level

Tbio 49 | 10,625
Tchem 38 | 1,890
Tclin 5 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, incomple... 4 | 260
abnormal behavior 2 | 226
abnormal kidney morphology 2 | 30
decreased mean corpuscular hem... 2 | 34
female infertility 2 | 34
increased circulating alanine ... 2 | 11
increased circulating aspartat... 2 | 17
preweaning lethality, complete... 2 | 633
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal lymph node morphology 1 | 3
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal spinal cord morpholog... 1 | 8
abnormal thoracic cage shape 1 | 3
absent seminal vesicle 1 | 2
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased mean platelet volume 1 | 12
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased hematocrit 1 | 36
increased kidney weight 1 | 4
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased startle reflex 1 | 38
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
shortened QRS complex duration 1 | 1
tremors 1 | 34

Disease

Cholestasis 93 | 93
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 92 | 18,473
Liver and Pancreas 92 | 18,136
Nervous System 91 | 18,561
Urinary Tract 91 | 18,444
Endocrine System 90 | 18,512
Female tissues 90 | 18,647
Blood and immune system 89 | 17,995
Male tissues 89 | 17,969
Skin and soft tissues 89 | 18,115
Cardiovascular System 88 | 17,958
Respiratory system 86 | 17,484

Target Family

Non-IDG 38 | 11,969
Transporter 20 | 473
Enzyme 19 | 4,146
Nuclear Receptor 6 | 48
Transcription Factor 6 | 1,400
GPCR 2 | 408
Kinase 2 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell cycle control protein 50A TMEM30A Tbio Non-IDG -1.01830 9.66 25
Organic solute transporter subunit beta SLC51B Tbio Transporter -1.34704 19.7 30
Organic solute transporter subunit alpha SLC51A Tchem Transporter -1.89090 81.9 58
Solute carrier family 23 member 1 SLC23A1 Tbio Transporter -1.80065 57.1 54
Putative gamma-glutamyltranspeptidase 3 GGT3P Tdark Enzyme -3.06984 1598.6 0
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.23809 1522.6 484
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase CYP8B1 Tbio Enzyme -1.62014 38.3 100
Pro-opiomelanocortin POMC Tbio Non-IDG -4.55455 36028.8 1100
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Solute carrier organic anion transporter family member 1B1 SLCO1B1 Tchem Transporter -2.74527 533.5 99