Development Level

Tbio 108 | 11,178
Tchem 69 | 1,885
Tclin 43 | 612
Tdark 3 | 6,569

IMPC Phenotype

preweaning lethality, complete... 16 | 979
decreased vertical activity 11 | 208
embryonic lethality prior to o... 9 | 239
embryonic lethality prior to t... 8 | 278
preweaning lethality, incomple... 7 | 499
abnormal behavior 5 | 298
abnormal embryo size 4 | 220
abnormal heart morphology 4 | 162
decreased bone mineral content 4 | 151
decreased circulating glucose ... 4 | 126
embryonic growth retardation 4 | 106
enlarged heart 4 | 210
abnormal bone structure 3 | 187
decreased circulating LDL chol... 3 | 38
decreased grip strength 3 | 116
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased circulating triglyce... 3 | 42
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
pale yolk sac 3 | 25
small superior vagus ganglion 3 | 74
tremors 3 | 39
abnormal allantois morphology 2 | 8
abnormal chorioallantoic fusio... 2 | 8
abnormal embryo turning 2 | 31
abnormal neural tube morpholog... 2 | 12
abnormal seminal vesicle morph... 2 | 114
abnormal visceral yolk sac mor... 2 | 6
abnormal vitelline vasculature... 2 | 6
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating phosphat... 2 | 27
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased heart weight 2 | 27
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
edema 2 | 59
enlarged uterus 2 | 11
hemorrhage 2 | 23
increased circulating bilirubi... 2 | 16
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased startle reflex 2 | 112
pallor 2 | 34
abnormal blood vessel morpholo... 1 | 5
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart looping 1 | 5
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
polycystic kidney 1 | 15
shortened RR interval 1 | 17
small testis 1 | 58
syndactyly 1 | 23

Disease

Cerebrovascular disease 223 | 223
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 220 | 18,159
Digestive Tract 219 | 17,369
Liver and Pancreas 218 | 16,750
Skin and soft tissues 217 | 17,230
Urinary Tract 217 | 16,678
Female tissues 216 | 17,400
Male tissues 215 | 17,142
Blood and immune system 213 | 16,909
Respiratory system 211 | 16,393
Nervous System 207 | 16,725
Cardiovascular System 188 | 15,192

Target Family

Non-IDG 130 | 12,091
Enzyme 52 | 4,145
GPCR 13 | 408
Transcription Factor 8 | 1,400
Kinase 7 | 634
Transporter 6 | 473
Ion Channel 4 | 344
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plasminogen-like protein A PLGLA Tdark Non-IDG -3.96245 15129.1 0
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Solute carrier family 12 member 3 SLC12A3 Tclin Transporter -2.82971 634.2 167
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
2,4-dienoyl-CoA reductase, mitochondrial DECR1 Tbio Enzyme -4.22091 15887.9 151
Alpha-2B adrenergic receptor ADRA2B Tclin GPCR -2.15839 139.8 0
Aquaporin-4 AQP4 Tchem Non-IDG -3.33435 2159.1 358
Claudin-5 CLDN5 Tbio Non-IDG -2.58968 349.4 300
Serine dehydratase-like SDSL Tbio Enzyme -2.81127 638.6 190
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259