Development Level

Tbio 130 | 11,445
Tchem 33 | 1,598
Tclin 11 | 613
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 22 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 9 | 278
abnormal behavior 8 | 298
abnormal embryo size 6 | 220
hyperactivity 6 | 148
preweaning lethality, incomple... 5 | 499
decreased bone mineral content 4 | 151
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged heart 4 | 210
abnormal heart morphology 3 | 162
abnormal midbrain development 3 | 20
abnormal neural tube closure 3 | 46
decreased grip strength 3 | 116
decreased heart rate 3 | 18
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
decreased respiratory quotient 3 | 16
embryonic growth retardation 3 | 106
enlarged lymph nodes 3 | 37
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased body length 3 | 32
increased circulating alkaline... 3 | 122
limb grasping 3 | 41
prenatal lethality prior to he... 3 | 87
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
absent adrenal gland 2 | 2
anophthalmia 2 | 33
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
edema 2 | 59
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased startle reflex 2 | 112
male infertility 2 | 123
microphthalmia 2 | 26
premature death 2 | 5
prenatal lethality 2 | 28
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal esophagus morphology 1 | 5
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
abnormal vibrissa morphology 1 | 25
absent lymph nodes 1 | 3
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
enlarged thymus 1 | 5
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
persistence of hyaloid vascula... 1 | 33
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39

Disease

Cerebral atrophy 178 | 178
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 178 | 18,159
Digestive Tract 177 | 17,369
Nervous System 177 | 16,725
Blood and immune system 176 | 16,909
Female tissues 176 | 17,400
Liver and Pancreas 175 | 16,750
Male tissues 175 | 17,142
Respiratory system 175 | 16,393
Skin and soft tissues 175 | 17,230
Urinary Tract 175 | 16,678
Cardiovascular System 171 | 15,192

Target Family

Enzyme 80 | 4,145
Non-IDG 62 | 12,091
Kinase 13 | 634
Transporter 10 | 473
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Ion Channel 3 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Required for meiotic nuclear division protein 1 homolog RMND1 Tbio Non-IDG -0.98615 10.0 63
Tetratricopeptide repeat protein 19, mitochondrial TTC19 Tbio Non-IDG -0.95371 10.6 38
Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A Tchem Kinase -2.68760 506.6 336
Vacuolar protein sorting-associated protein 13A VPS13A Tbio Non-IDG -2.19966 172.3 22
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307
DNA-directed RNA polymerase III subunit RPC2 POLR3B Tbio Enzyme -1.25377 19.0 105
WD repeat domain phosphoinositide-interacting protein 4 WDR45 Tbio Non-IDG -1.29355 17.4 93
Methionine synthase MTR Tbio Enzyme -2.56900 300.2 87