Development Level

Tbio 79 | 10,625
Tchem 15 | 1,890
Tdark 13 | 7,003
Tclin 5 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal bone structure 4 | 131
decreased bone mineral content 4 | 157
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 121
decreased lean body mass 3 | 195
increased circulating alkaline... 3 | 119
increased circulating sodium l... 3 | 71
preweaning lethality, complete... 3 | 633
abnormal behavioral response t... 2 | 52
abnormal sleep behavior 2 | 63
decreased CD4-positive, CD25-p... 2 | 24
decreased body length 2 | 108
decreased fasted circulating g... 2 | 49
decreased lumbar vertebrae num... 2 | 62
decreased mature B cell number 2 | 25
increased effector memory CD4-... 2 | 15
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
increased memory CD4-positive,... 2 | 3
increased sacral vertebrae num... 2 | 62
abnormal behavior 1 | 226
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin coloration 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
absent vibrissae 1 | 14
decreased B cell number 1 | 30
decreased CD8-positive, naive ... 1 | 5
decreased NK T cell number 1 | 28
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 19
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased thoracic vertebrae n... 1 | 7
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged testis 1 | 1
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased neutrophil cell numb... 1 | 15
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
tremors 1 | 34
vertebral fusion 1 | 23

Disease

Celiac disease 112 | 112
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 109 | 18,473
Endocrine System 109 | 18,512
Urinary Tract 109 | 18,444
Female tissues 108 | 18,647
Blood and immune system 107 | 17,995
Nervous System 107 | 18,561
Cardiovascular System 106 | 17,958
Liver and Pancreas 106 | 18,136
Male tissues 106 | 17,969
Respiratory system 105 | 17,484
Skin and soft tissues 105 | 18,115

Target Family

Non-IDG 62 | 11,969
Enzyme 28 | 4,146
Transcription Factor 12 | 1,400
GPCR 4 | 408
Transporter 3 | 473
Kinase 2 | 634
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plexin-A4 PLXNA4 Tbio Non-IDG -1.39542 24.7 96
Zinc finger protein 639 ZNF639 Tbio Transcription Factor -0.56820 5.21 44
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
Interleukin-18 receptor 1 IL18R1 Tbio Non-IDG -1.47717 28.0 429
Interleukin-21 IL21 Tbio Non-IDG -2.42606 328.1 519
Tyrosine-protein phosphatase non-receptor type 2 PTPN2 Tchem Enzyme -2.49223 269.5 174
Tetratricopeptide repeat protein 34 TTC34 Tdark Non-IDG 0.44 0.27 48
Ataxin-2 ATXN2 Tbio Non-IDG -2.28893 208.6 178
Unconventional myosin-IXb MYO9B Tbio Non-IDG -1.66965 54.7 76
FERM domain-containing protein 4B FRMD4B Tdark Non-IDG -0.61101 4.73 31