Development Level

Tbio 81 | 10,625
Tchem 15 | 1,890
Tclin 4 | 602
Tdark 4 | 7,003

IMPC Phenotype

abnormal behavior 3 | 226
embryonic lethality prior to t... 3 | 187
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal neural tube closure 2 | 37
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
decreased body weight 2 | 174
decreased circulating amylase ... 2 | 24
decreased circulating calcium ... 2 | 33
decreased circulating triglyce... 2 | 83
decreased prepulse inhibition 2 | 52
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased body weight 2 | 42
increased circulating alkaline... 2 | 119
preweaning lethality, complete... 2 | 633
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal body size 1 | 1
abnormal bone mineralization 1 | 55
abnormal embryo turning 1 | 15
abnormal epididymis morphology 1 | 31
abnormal eyelid aperture 1 | 3
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal midbrain development 1 | 22
abnormal radius morphology 1 | 8
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal social-conspecific in... 1 | 3
abnormal tail bud morphology 1 | 6
abnormal tail morphology 1 | 17
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
anophthalmia 1 | 20
convulsive seizures 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart rate 1 | 10
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased mean platelet volume 1 | 12
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic growth retardation 1 | 28
enlarged epididymis 1 | 27
hydrometra 1 | 13
improved glucose tolerance 1 | 56
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating chloride... 1 | 43
increased circulating potassiu... 1 | 31
increased coping response 1 | 3
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased heart rate 1 | 17
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
microphthalmia 1 | 15
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
short tibia 1 | 82
shortened QRS complex duration 1 | 1
shortened ST segment 1 | 9
small epididymis 1 | 3
small seminal vesicle 1 | 6
small testis 1 | 37
thick tail 1 | 1

Disease

Cataract 104 | 104
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Endocrine System 104 | 18,511
Nervous System 104 | 18,560
Digestive Tract 102 | 18,472
Female tissues 102 | 18,646
Urinary Tract 102 | 18,443
Skin and soft tissues 101 | 18,114
Liver and Pancreas 98 | 18,135
Male tissues 98 | 17,968
Blood and immune system 97 | 17,994
Cardiovascular System 96 | 17,957
Respiratory system 92 | 17,483

Target Family

Non-IDG 57 | 11,969
Enzyme 26 | 4,146
Transcription Factor 7 | 1,400
Kinase 6 | 634
Transporter 5 | 473
Epigenetic 2 | 242
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon-induced transmembrane protein 2 IFITM2 Tbio Non-IDG -2.21851 158.1 111
Sorbitol dehydrogenase SORD Tchem Enzyme -2.17326 129.8 298
Alpha-crystallin A chain CRYAA Tbio Non-IDG -2.83468 658.4 164
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.86562 689.3 377
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.78535 625.6 162
Heat shock factor protein 4 HSF4 Tbio Transcription Factor -2.80080 629.1 217
Protein NDRG2 NDRG2 Tbio Non-IDG -1.89119 127.5 268
Myotonin-protein kinase DMPK Tchem Kinase -2.69587 476.6 171
Inositol polyphosphate 5-phosphatase OCRL-1 OCRL Tbio Enzyme -2.17795 160.1 198
Ephrin type-A receptor 2 EPHA2 Tclin Kinase -2.87482 785.1 704