Development Level

Tbio 160 | 11,178
Tdark 40 | 6,569
Tchem 26 | 1,885
Tclin 14 | 612

Collection

GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 20 | 979
abnormal behavior 6 | 298
preweaning lethality, incomple... 5 | 499
decreased mean corpuscular vol... 4 | 79
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
increased fasted circulating g... 4 | 76
decreased body weight 3 | 161
decreased grip strength 3 | 116
decreased heart left ventricle... 3 | 28
decreased lymphocyte cell numb... 3 | 83
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
hypoactivity 3 | 132
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal behavioral response t... 2 | 66
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal sleep behavior 2 | 70
cataract 2 | 92
convulsive seizures 2 | 13
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
enlarged heart 2 | 210
enlarged uterus 2 | 11
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating iron lev... 2 | 30
increased circulating phosphat... 2 | 26
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
limb grasping 2 | 41
male infertility 2 | 123
short tibia 2 | 97
small superior vagus ganglion 2 | 74
thin ventricular wall 2 | 24
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased startle reflex 1 | 112
small kidney 1 | 16
small testis 1 | 58
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Cardiovascular system disease 240 | 240
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 234 | 18,159
Female tissues 230 | 17,400
Skin and soft tissues 225 | 17,230
Digestive Tract 224 | 17,369
Male tissues 223 | 17,142
Liver and Pancreas 218 | 16,750
Nervous System 218 | 16,725
Urinary Tract 218 | 16,678
Blood and immune system 215 | 16,909
Respiratory system 208 | 16,393
Cardiovascular System 196 | 15,192

Target Family

Non-IDG 137 | 12,091
Enzyme 55 | 4,145
Transcription Factor 15 | 1,400
Transporter 10 | 473
GPCR 7 | 408
Ion Channel 6 | 344
Kinase 5 | 634
Epigenetic 2 | 242
oGPCR 2 | 421
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acid-sensing ion channel 2 ASIC2 Tbio Ion Channel -2.49683 295.8 140
Junctional protein associated with coronary artery disease JCAD Tbio Non-IDG -0.81180 6.70 18
Uncharacterized protein C6orf10 C6orf10 Tdark Non-IDG -0.51955 3.93 23
Solute carrier family 12 member 3 SLC12A3 Tclin Transporter -2.82971 634.2 167
IQ domain-containing protein J IQCJ Tdark Non-IDG -0.09691 0.85 113
Ribosome biogenesis protein WDR12 WDR12 Tbio Non-IDG -1.28968 20.5 125
Transmembrane protein 241 TMEM241 Tdark Non-IDG 0.00000 1.39 21
Enolase 4 ENO4 Tdark Enzyme -0.21160 1.85 71
Unconventional myosin-Ih MYO1H Tdark Non-IDG -0.56690 3.82 16
Putative sodium-coupled neutral amino acid transporter 11 SLC38A11 Tdark Transporter 1.18 0.07 7