Development Level

Tbio 167 | 11,651
Tdark 42 | 6,593
Tchem 22 | 1,388
Tclin 15 | 612

Collection

RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 20 | 979
abnormal behavior 6 | 298
preweaning lethality, incomple... 5 | 499
decreased mean corpuscular vol... 4 | 79
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
increased circulating alkaline... 4 | 122
increased fasted circulating g... 4 | 76
decreased body length 3 | 101
decreased body weight 3 | 161
decreased grip strength 3 | 116
decreased heart left ventricle... 3 | 28
decreased lymphocyte cell numb... 3 | 83
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
hypoactivity 3 | 132
increased circulating choleste... 3 | 66
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal behavioral response t... 2 | 66
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal sleep behavior 2 | 70
cataract 2 | 92
convulsive seizures 2 | 13
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
enlarged heart 2 | 210
enlarged uterus 2 | 11
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating iron lev... 2 | 30
increased circulating phosphat... 2 | 26
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
limb grasping 2 | 41
male infertility 2 | 123
short tibia 2 | 97
small superior vagus ganglion 2 | 74
thin ventricular wall 2 | 24
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased startle reflex 1 | 112
small kidney 1 | 16
small testis 1 | 58
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Cardiovascular system disease 246 | 246
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 240 | 18,159
Female tissues 236 | 17,400
Skin and soft tissues 231 | 17,230
Digestive Tract 230 | 17,369
Male tissues 229 | 17,142
Liver and Pancreas 224 | 16,750
Nervous System 224 | 16,725
Urinary Tract 224 | 16,678
Blood and immune system 221 | 16,909
Respiratory system 214 | 16,393
Cardiovascular System 201 | 15,192

Target Family

Non-IDG 138 | 12,091
Enzyme 58 | 4,145
Transcription Factor 17 | 1,400
Transporter 10 | 473
GPCR 7 | 408
Ion Channel 6 | 344
Kinase 5 | 634
Epigenetic 2 | 242
oGPCR 2 | 421
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Zinc finger protein 518B ZNF518B Tdark Non-IDG -0.25756 2.11 12
Angiopoietin-like protein 8 ANGPTL8 Tbio Non-IDG -2.07410 141.2 93
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Formin-like protein 2 FMNL2 Tbio Non-IDG -1.22907 18.1 74
Nuclear-interacting partner of ALK ZC3HC1 Tbio Non-IDG -2.13812 136.0 171
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.09168 112.5 175
CDKN2A-interacting protein CDKN2AIP Tbio Non-IDG -0.74312 7.49 147
Chordin-like protein 1 CHRDL1 Tbio Non-IDG -1.99743 97.9 191