Development Level

Tbio 94 | 11,445
Tclin 14 | 613
Tchem 7 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 14 | 979
increased heart weight 5 | 62
decreased body weight 4 | 161
abnormal embryo size 3 | 220
edema 3 | 59
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased cardiac muscle contr... 2 | 11
decreased circulating amylase ... 2 | 28
decreased circulating iron lev... 2 | 32
decreased lean body mass 2 | 135
dilated heart left ventricle 2 | 11
embryonic lethality prior to o... 2 | 239
increased circulating sodium l... 2 | 71
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
tremors 2 | 39
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal response to new envir... 1 | 10
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
corneal opacity 1 | 32
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased erythrocyte cell num... 1 | 39
increased heart left ventricle... 1 | 4
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
long tibia 1 | 25
narrow eye opening 1 | 12
prenatal lethality 1 | 28
respiratory system phenotype 1 | 2
short tibia 1 | 97
small adrenal glands 1 | 16
thick ventricular wall 1 | 7

Disease

Cardiomyopathy 116 | 116
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Female tissues 115 | 17,400
Endocrine System 114 | 18,159
Male tissues 113 | 17,142
Cardiovascular System 112 | 15,192
Digestive Tract 112 | 17,369
Liver and Pancreas 112 | 16,750
Blood and immune system 111 | 16,909
Skin and soft tissues 111 | 17,230
Urinary Tract 110 | 16,678
Nervous System 106 | 16,725
Respiratory system 105 | 16,393

Target Family

Non-IDG 68 | 12,091
Enzyme 21 | 4,145
Kinase 9 | 634
Transcription Factor 7 | 1,400
Ion Channel 6 | 344
Transporter 4 | 473
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Protein MTO1 homolog, mitochondrial MTO1 Tbio Non-IDG -2.45185 260.9 53
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
Ectopic P granules protein 5 homolog EPG5 Tbio Non-IDG -1.36198 23.3 33
GATA zinc finger domain-containing protein 1 GATAD1 Tbio Transcription Factor -0.86776 8.02 116
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243