Development Level

Tbio 66 | 11,445
Tchem 27 | 1,598
Tclin 16 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased fasted circulating g... 3 | 65
abnormal heart morphology 2 | 162
decreased total body fat amoun... 2 | 207
increased heart weight 2 | 62
increased startle reflex 2 | 112
long tibia 2 | 25
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal epididymis morphology 1 | 42
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased coping response 1 | 8
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased large unstained cell... 1 | 11
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired righting response 1 | 26
increased circulating chloride... 1 | 41
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
short tibia 1 | 97

Disease

Cardiomyopathies 110 | 110
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Urinary Tract 110 | 16,678
Digestive Tract 109 | 17,369
Endocrine System 109 | 18,159
Liver and Pancreas 109 | 16,750
Blood and immune system 108 | 16,909
Female tissues 108 | 17,400
Male tissues 108 | 17,142
Skin and soft tissues 108 | 17,230
Respiratory system 106 | 16,393
Nervous System 103 | 16,725
Cardiovascular System 102 | 15,192

Target Family

Non-IDG 55 | 12,091
Enzyme 35 | 4,145
Kinase 10 | 634
GPCR 4 | 408
Ion Channel 2 | 344
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Ectopic P granules protein 5 homolog EPG5 Tbio Non-IDG -1.36198 23.3 33
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -2.00418 105.2 236
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Wolframin WFS1 Tbio Non-IDG -2.40006 260.2 118
Arylsulfatase B ARSB Tbio Enzyme -2.51626 314.5 216
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.51690 305.3 99
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.19082 152.8 117
Cardiac phospholamban PLN Tbio Non-IDG -1.93701 85.8 365