Development Level

Tbio 122 | 11,445
Tchem 76 | 1,598
Tclin 29 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 19 | 979
abnormal behavior 7 | 298
embryonic lethality prior to t... 7 | 278
abnormal embryo size 5 | 220
decreased body weight 5 | 161
decreased lean body mass 5 | 135
decreased mean corpuscular vol... 5 | 79
embryonic lethality prior to o... 5 | 239
increased startle reflex 5 | 112
decreased bone mineral density 4 | 126
enlarged heart 4 | 210
hydrometra 4 | 53
hyperactivity 4 | 148
hypoactivity 4 | 132
increased circulating choleste... 4 | 66
increased total body fat amoun... 4 | 134
preweaning lethality, incomple... 4 | 499
decreased bone mineral content 3 | 151
decreased circulating serum al... 3 | 82
decreased heart weight 3 | 27
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
enlarged uterus 3 | 11
increased circulating HDL chol... 3 | 80
increased mean corpuscular hem... 3 | 96
prolonged ST segment 3 | 36
short tibia 3 | 97
small superior vagus ganglion 3 | 74
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal forebrain development 2 | 20
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal locomotor behavior 2 | 24
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 31
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
female infertility 2 | 60
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased circulating alanine ... 2 | 13
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
male infertility 2 | 123
microphthalmia 2 | 26
prolonged QT interval 2 | 38
shortened RR interval 2 | 17
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal spine curvature 1 | 9
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased pulmonary respirator... 1 | 5
edema 1 | 59
enlarged spleen 1 | 41
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased lactate dehydrogenas... 1 | 3
increased monocyte cell number 1 | 63
limb grasping 1 | 41
premature death 1 | 5
prenatal lethality 1 | 28
small kidney 1 | 16
tremors 1 | 39

Disease

Carcinoma, Hepatocellular 228 | 228
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Liver and Pancreas 223 | 16,750
Endocrine System 222 | 18,159
Urinary Tract 221 | 16,678
Digestive Tract 220 | 17,369
Skin and soft tissues 220 | 17,230
Female tissues 219 | 17,400
Male tissues 218 | 17,142
Nervous System 214 | 16,725
Blood and immune system 213 | 16,909
Respiratory system 211 | 16,393
Cardiovascular System 202 | 15,192

Target Family

Non-IDG 95 | 12,091
Enzyme 73 | 4,145
Transcription Factor 26 | 1,400
Kinase 17 | 634
Nuclear Receptor 7 | 48
Transporter 5 | 473
Epigenetic 4 | 242
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
6-phosphogluconate dehydrogenase, decarboxylating PGD Tchem Enzyme -2.56683 355.7 211
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Glycine N-methyltransferase GNMT Tbio Enzyme -1.56517 40.8 216
ATP-citrate synthase ACLY Tchem Enzyme -2.82704 654.3 332
Fatty acid-binding protein, epidermal FABP5 Tchem Non-IDG -1.94229 141.2 226