Development Level

Tbio 45 | 11,445
Tchem 15 | 1,598
Tclin 10 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
abnormal bone structure 2 | 187
abnormal femur morphology 2 | 14
abnormal vertebrae morphology 2 | 18
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating calcium ... 2 | 36
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebral arch morpho... 1 | 9
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged uterus 1 | 11
eyelids fail to open 1 | 3
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
kyphosis 1 | 5
long tail 1 | 1
mammalian phenotype 1 | 17
small superior vagus ganglion 1 | 74
thick tail 1 | 1

Disease

Calcinosis 70 | 70
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 69 | 17,369
Urinary Tract 68 | 16,678
Male tissues 67 | 17,142
Skin and soft tissues 67 | 17,230
Blood and immune system 66 | 16,909
Endocrine System 66 | 18,159
Liver and Pancreas 66 | 16,750
Nervous System 66 | 16,725
Female tissues 65 | 17,400
Respiratory system 63 | 16,393
Cardiovascular System 53 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 19 | 4,145
Transporter 6 | 473
Ion Channel 3 | 344
Kinase 3 | 634
Epigenetic 1 | 242
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Exosome component 10 EXOSC10 Tbio Non-IDG -2.45249 279.1 123
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.29276 197.3 107
Multidrug resistance-associated protein 6 ABCC6 Tbio Transporter -2.71911 547.1 100
CAAX prenyl protease 1 homolog ZMPSTE24 Tbio Enzyme -2.10187 125.8 321
Glyoxylate reductase/hydroxypyruvate reductase GRHPR Tbio Enzyme -1.91645 81.8 157