Development Level

Tbio 80 | 11,178
Tchem 25 | 1,885
Tdark 6 | 6,569
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
abnormal bone structure 2 | 187
abnormal gait 2 | 69
decreased body weight 2 | 161
decreased circulating chloride... 2 | 30
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal clavicle morphology 1 | 6
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased granulocyte number 1 | 6
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
unresponsive to tactile stimul... 1 | 8

Disease

COPD 114 | 114
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 114 | 17,369
Respiratory system 114 | 16,393
Skin and soft tissues 114 | 17,230
Urinary Tract 114 | 16,678
Blood and immune system 113 | 16,909
Endocrine System 113 | 18,159
Female tissues 113 | 17,400
Liver and Pancreas 113 | 16,750
Male tissues 112 | 17,142
Nervous System 111 | 16,725
Cardiovascular System 110 | 15,192

Target Family

Non-IDG 69 | 12,091
Enzyme 24 | 4,145
Kinase 9 | 634
Transcription Factor 7 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
S-adenosylmethionine synthase isoform type-2 MAT2A Tbio Enzyme -1.91969 84.1 242
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Ras-related protein Rab-6A RAB6A Tbio Enzyme -2.09488 134.5 207
Transcription factor E3 TFE3 Tbio Transcription Factor -2.43611 297.2 314
C-C motif chemokine 8 CCL8 Tbio Non-IDG -2.14856 127.9 298
ATP-dependent RNA helicase DDX3X DDX3X Tchem Enzyme -2.32036 221.7 479
UPF0687 protein C20orf27 C20orf27 Tdark Non-IDG 0.00000 29
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Gelsolin GSN Tbio Non-IDG -3.11676 1340.4 481
Vinexin SORBS3 Tbio Non-IDG -1.52089 35.1 57