Development Level

Tbio 38 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613
Tdark 3 | 6,588

IMPC Phenotype

increased circulating alkaline... 5 | 122
abnormal behavior 3 | 298
hyperactivity 3 | 148
preweaning lethality, incomple... 3 | 499
abnormal spleen morphology 2 | 55
cardiovascular system phenotyp... 2 | 36
decreased circulating serum al... 2 | 82
decreased hemoglobin content 2 | 68
decreased vertical activity 2 | 208
enlarged lymph nodes 2 | 37
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating phosphat... 2 | 26
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
absent adrenal gland 1 | 2
cataract 1 | 92
decreased body weight 1 | 161
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased pulmonary respirator... 1 | 5
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased coping response 1 | 4
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
long tibia 1 | 25
prenatal lethality 1 | 28
shortened QT interval 1 | 4
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Bulbous nasal tip 48 | 48
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Skin and soft tissues 47 | 17,230
Blood and immune system 46 | 16,909
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Urinary Tract 45 | 16,678
Cardiovascular System 44 | 15,192
Respiratory system 43 | 16,393

Target Family

Non-IDG 27 | 12,091
Enzyme 11 | 4,145
Transcription Factor 6 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Calmodulin-binding transcription activator 1 CAMTA1 Tbio Transcription Factor -1.48601 33.1 26
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Helicase SRCAP SRCAP Tbio Enzyme -1.89315 84.2 67
Platelet glycoprotein Ib beta chain GP1BB Tbio Non-IDG -1.79873 57.4 87