Development Level

Tchem 39 | 1,890
Tbio 33 | 10,625
Tclin 15 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased grip strength 4 | 123
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal epididymis morphology 2 | 31
abnormal testis morphology 2 | 30
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
enlarged epididymis 2 | 27
hypoactivity 2 | 89
increased circulating alkaline... 2 | 119
increased lean body mass 2 | 107
preweaning lethality, complete... 2 | 633
short tibia 2 | 82
small testis 2 | 37
tremors 2 | 34
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retinal inner nuclear... 1 | 5
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
absent seminal vesicle 1 | 2
decreased B cell number 1 | 30
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased thermal nociceptive ... 1 | 4
decreased total retina thickne... 1 | 20
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased circulating free fat... 1 | 17
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased hematocrit 1 | 36
increased leukocyte cell numbe... 1 | 37
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62

Disease

Brain Ischemia 87 | 87
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 85 | 17,995
Digestive Tract 85 | 18,473
Female tissues 85 | 18,647
Nervous System 85 | 18,561
Skin and soft tissues 85 | 18,115
Urinary Tract 85 | 18,444
Cardiovascular System 84 | 17,958
Endocrine System 84 | 18,512
Liver and Pancreas 84 | 18,136
Male tissues 84 | 17,969
Respiratory system 84 | 17,484

Target Family

Non-IDG 42 | 11,969
Enzyme 19 | 4,146
Transcription Factor 8 | 1,400
Transporter 6 | 473
Ion Channel 5 | 341
Kinase 5 | 634
GPCR 2 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.20483 1368.4 194
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -1.97359 79.2 511
Interleukin-12 receptor subunit beta-1 IL12RB1 Tbio Non-IDG -2.31330 207.1 227
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.04744 808.6 1868
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.37638 17.8 34
Neuronal migration protein doublecortin DCX Tbio Non-IDG -3.00218 886.4 413
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.62805 3186.8 1232
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.66762 4846.8 245