Development Level

Tbio 115 | 11,445
Tchem 21 | 1,598
Tclin 11 | 613
Tdark 9 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 24 | 979
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
embryonic lethality prior to o... 4 | 239
increased heart weight 4 | 62
increased startle reflex 4 | 112
embryonic growth retardation 3 | 106
abnormal heart morphology 2 | 162
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
increased body weight 2 | 25
increased fasted circulating g... 2 | 76
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
edema 1 | 59
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
protruding tongue 1 | 3
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small superior vagus ganglion 1 | 74
unresponsive to tactile stimul... 1 | 8

Disease

Brachydactyly 156 | 156
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 150 | 17,369
Endocrine System 150 | 18,159
Male tissues 150 | 17,142
Female tissues 149 | 17,400
Skin and soft tissues 149 | 17,230
Urinary Tract 147 | 16,678
Liver and Pancreas 146 | 16,750
Blood and immune system 144 | 16,909
Nervous System 144 | 16,725
Respiratory system 144 | 16,393
Cardiovascular System 141 | 15,192

Target Family

Non-IDG 83 | 12,091
Enzyme 27 | 4,145
Transcription Factor 19 | 1,400
Kinase 15 | 634
Epigenetic 6 | 242
Ion Channel 3 | 344
Transporter 2 | 473
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Lysine-specific demethylase 5C KDM5C Tchem TF/Epigenetic -1.94004 86.4 135
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Zinc finger transcription factor Trps1 TRPS1 Tbio Transcription Factor -1.98756 107.0 69
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.78912 62.9 93
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RHNO1 Tbio Non-IDG -3.20363 1560.8 3
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23