Development Level

Tbio 154 | 11,445
Tclin 45 | 613
Tchem 29 | 1,598
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 34 | 979
abnormal behavior 7 | 298
embryonic lethality prior to t... 6 | 278
decreased body weight 5 | 161
decreased circulating choleste... 5 | 93
embryonic lethality prior to o... 5 | 239
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged heart 4 | 210
hyperactivity 4 | 148
preweaning lethality, incomple... 4 | 499
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating fructosa... 3 | 30
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
abnormal snout morphology 2 | 23
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased lactate dehydrogenas... 2 | 16
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased spleen weight 2 | 10
enlarged kidney 2 | 14
enlarged spleen 2 | 41
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged heart atrium 1 | 4
enlarged urinary bladder 1 | 8
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small kidney 1 | 16
small testis 1 | 58
syndactyly 1 | 23
urinary bladder obstruction 1 | 4

Disease

Blepharoptosis 231 | 231
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 229 | 18,159
Skin and soft tissues 228 | 17,230
Digestive Tract 227 | 17,369
Male tissues 227 | 17,142
Female tissues 225 | 17,400
Blood and immune system 224 | 16,909
Nervous System 224 | 16,725
Urinary Tract 224 | 16,678
Liver and Pancreas 221 | 16,750
Cardiovascular System 219 | 15,192
Respiratory system 219 | 16,393

Target Family

Non-IDG 91 | 12,091
Enzyme 79 | 4,145
Transcription Factor 23 | 1,400
Kinase 12 | 634
Epigenetic 8 | 242
Ion Channel 8 | 344
Transporter 8 | 473
GPCR 1 | 408
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 Tclin Enzyme -1.42734 26.2 214
Cytochrome c oxidase assembly protein COX15 homolog COX15 Tbio Enzyme -1.37513 23.0 104
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 Tclin Enzyme -2.43529 263.5 165
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197