Development Level

Tbio 59 | 10,625
Tchem 34 | 1,890
Tclin 11 | 602
Tdark 5 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal sleep behavior 3 | 63
abnormal behavior 2 | 226
abnormal epididymis morphology 2 | 31
abnormal spleen morphology 2 | 36
abnormal testis morphology 2 | 30
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating aspartat... 2 | 27
decreased circulating insulin ... 2 | 75
enlarged epididymis 2 | 27
enlarged heart 2 | 111
enlarged spleen 2 | 26
increased fasted circulating g... 2 | 68
preweaning lethality, complete... 2 | 633
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal retinal pigmentation 1 | 61
abnormal urinary bladder morph... 1 | 2
absent vibrissae 1 | 14
cataract 1 | 26
convulsive seizures 1 | 11
decreased CD4-positive, CD25-p... 1 | 24
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating fructosa... 1 | 31
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean platelet volume 1 | 12
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

Bladder Neoplasm 109 | 109
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 109 | 17,995
Endocrine System 109 | 18,512
Female tissues 109 | 18,647
Nervous System 109 | 18,561
Skin and soft tissues 109 | 18,115
Urinary Tract 109 | 18,444
Cardiovascular System 108 | 17,958
Digestive Tract 108 | 18,473
Male tissues 108 | 17,969
Liver and Pancreas 107 | 18,136
Respiratory system 107 | 17,484

Target Family

Non-IDG 43 | 11,971
Enzyme 36 | 4,146
Epigenetic 9 | 242
Transcription Factor 8 | 1,400
Kinase 5 | 634
Ion Channel 2 | 341
Nuclear Receptor 2 | 48
Transporter 2 | 473
TF/Epigenetic 1 | 38
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Calcium homeostasis modulator protein 1 CALHM1 Tbio Ion Channel -1.62156 47.0 81
Metallothionein-2 MT2A Tbio Non-IDG -2.42641 259.2 92
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Structural maintenance of chromosomes protein 1B SMC1B Tbio Non-IDG -1.26509 19.6 93
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Ubiquitin carboxyl-terminal hydrolase 7 USP7 Tchem Enzyme -2.17350 165.7 375
Lysine-specific demethylase 6A KDM6A Tchem Epigenetic -2.14014 144.5 92