Development Level

Tbio 385 | 11,445
Tchem 137 | 1,598
Tclin 111 | 613
Tdark 33 | 6,588

Collection

Ion Channel: IDG Consortium (T... 13 | 99
GPCR: IDG Consortium (Targets) 5 | 126
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 38 | 979
preweaning lethality, incomple... 26 | 499
decreased total body fat amoun... 21 | 207
abnormal behavior 19 | 298
increased lean body mass 15 | 172
embryonic lethality prior to t... 13 | 278
decreased body weight 12 | 161
decreased grip strength 12 | 116
abnormal bone structure 11 | 187
decreased circulating choleste... 11 | 93
decreased vertical activity 10 | 208
enlarged heart 10 | 210
increased total body fat amoun... 10 | 134
abnormal heart morphology 9 | 162
embryonic lethality prior to o... 9 | 239
hyperactivity 9 | 148
increased circulating alkaline... 9 | 122
abnormal seminal vesicle morph... 8 | 114
decreased circulating HDL chol... 8 | 68
decreased circulating alkaline... 8 | 46
decreased lean body mass 8 | 135
increased bone mineral content 8 | 108
short tibia 8 | 97
abnormal embryo size 7 | 220
decreased fasted circulating g... 7 | 65
hypoactivity 7 | 132
impaired glucose tolerance 7 | 75
increased circulating chloride... 7 | 41
increased circulating triglyce... 7 | 42
abnormal retina morphology 6 | 71
decreased bone mineral density 6 | 126
decreased lymphocyte cell numb... 6 | 83
decreased prepulse inhibition 6 | 82
improved glucose tolerance 6 | 79
increased circulating choleste... 6 | 66
abnormal bone mineralization 5 | 38
abnormal gait 5 | 69
abnormal lens morphology 5 | 81
decreased body length 5 | 101
decreased bone mineral content 5 | 151
decreased circulating glucose ... 5 | 126
decreased erythrocyte cell num... 5 | 62
decreased startle reflex 5 | 75
increased circulating sodium l... 5 | 71
increased mean corpuscular vol... 5 | 92
increased startle reflex 5 | 112
limb grasping 5 | 41
male infertility 5 | 123
abnormal behavioral response t... 4 | 66
abnormal epididymis morphology 4 | 42
abnormal eye morphology 4 | 68
abnormal locomotor behavior 4 | 24
cataract 4 | 92
decreased circulating LDL chol... 4 | 38
decreased circulating aspartat... 4 | 34
decreased circulating serum al... 4 | 82
decreased circulating triglyce... 4 | 79
edema 4 | 59
embryonic growth retardation 4 | 106
increased body weight 4 | 25
increased circulating alanine ... 4 | 13
increased hematocrit 4 | 46
increased monocyte cell number 4 | 63
prolonged ST segment 4 | 36
small testis 4 | 58
tremors 4 | 39
abnormal coat appearance 3 | 31
abnormal coat-hair pigmentatio... 3 | 64
abnormal skin morphology 3 | 50
abnormal testis morphology 3 | 43
corneal opacity 3 | 32
decreased caudal vertebrae num... 3 | 53
decreased circulating amylase ... 3 | 28
decreased circulating fructosa... 3 | 30
decreased circulating glycerol... 3 | 16
decreased circulating insulin ... 3 | 76
decreased mean corpuscular vol... 3 | 79
decreased neutrophil cell numb... 3 | 42
decreased pulmonary respirator... 3 | 5
increased blood urea nitrogen ... 3 | 48
increased circulating HDL chol... 3 | 80
increased circulating iron lev... 3 | 30
increased fasted circulating g... 3 | 76
increased heart weight 3 | 62
increased lymphocyte cell numb... 3 | 32
increased or absent threshold ... 3 | 101
increased red blood cell distr... 3 | 34
microphthalmia 3 | 26
prolonged QT interval 3 | 38
small superior vagus ganglion 3 | 74
thin ventricular wall 3 | 24
thrombocytopenia 3 | 56
abnormal sleep behavior 2 | 70
decreased circulating creatini... 2 | 39
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased prepulse inhibition 2 | 32
prenatal lethality prior to he... 2 | 87

Disease

Bipolar Disorder 666 | 666
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 645 | 18,159
Nervous System 629 | 16,725
Digestive Tract 624 | 17,369
Female tissues 618 | 17,400
Skin and soft tissues 615 | 17,230
Male tissues 610 | 17,142
Blood and immune system 603 | 16,909
Liver and Pancreas 602 | 16,750
Urinary Tract 602 | 16,678
Respiratory system 582 | 16,393
Cardiovascular System 534 | 15,192

Target Family

Non-IDG 282 | 12,091
Enzyme 149 | 4,145
Ion Channel 53 | 344
GPCR 50 | 408
Transcription Factor 47 | 1,400
Kinase 33 | 634
Transporter 29 | 473
Nuclear Receptor 12 | 48
Epigenetic 8 | 242
TF/Epigenetic 2 | 38
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Solute carrier family 45 member 4 SLC45A4 Tdark Transporter 0.30 0.50 12
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Trace amine-associated receptor 6 TAAR6 Tbio GPCR -2.06244 115.1 64
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Cadherin-7 CDH7 Tbio Non-IDG -1.37829 23.4 123