Development Level

Tbio 123 | 11,178
Tchem 29 | 1,885
Tclin 12 | 612
Tdark 9 | 6,569

Collection

GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
abnormal embryo size 5 | 220
decreased vertical activity 5 | 208
preweaning lethality, complete... 5 | 979
abnormal lens morphology 4 | 81
cataract 4 | 92
increased lean body mass 4 | 172
abnormal epididymis morphology 3 | 42
decreased lymphocyte cell numb... 3 | 83
enlarged epididymis 3 | 31
abnormal coat-hair pigmentatio... 2 | 64
abnormal facial morphology 2 | 17
abnormal head shape 2 | 10
abnormal heart morphology 2 | 162
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
absent vibrissae 2 | 12
decreased circulating calcium ... 2 | 36
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased red blood cell distr... 2 | 41
decreased threshold for audito... 2 | 26
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral content 2 | 108
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal locomotor activation 1 | 16
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent teeth 1 | 3
anophthalmia 1 | 33
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small kidney 1 | 16
stereotypic behavior 1 | 3
thrombocytosis 1 | 27
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Barrett's esophagus 173 | 173
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 171 | 17,369
Endocrine System 170 | 18,159
Blood and immune system 169 | 16,909
Female tissues 169 | 17,400
Liver and Pancreas 169 | 16,750
Skin and soft tissues 169 | 17,230
Urinary Tract 169 | 16,678
Male tissues 168 | 17,142
Nervous System 166 | 16,725
Respiratory system 165 | 16,393
Cardiovascular System 151 | 15,192

Target Family

Non-IDG 97 | 12,091
Enzyme 42 | 4,145
Transporter 12 | 473
Transcription Factor 8 | 1,400
Kinase 7 | 634
GPCR 3 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin, type I cytoskeletal 17 KRT17 Tbio Non-IDG -2.43909 265.8 711
Pirin PIR Tchem Non-IDG -2.72312 503.8 154
Ribosome-binding protein 1 RRBP1 Tbio Non-IDG -2.64530 433.3 157
Coactosin-like protein COTL1 Tbio Non-IDG -1.29261 19.3 205
Trefoil factor 2 TFF2 Tbio Non-IDG -2.38948 238.3 219
Nuclear receptor subfamily 4 group A member 2 NR4A2 Tchem Nuclear Receptor -2.59490 415.4 307
Transcription factor 20 TCF20 Tbio Epigenetic -2.47692 295.2 33
Trefoil factor 1 TFF1 Tbio Non-IDG -2.40517 263.2 481
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter SLC35D1 Tbio Transporter -0.77614 5.86 105
Polypeptide N-acetylgalactosaminyltransferase 10 GALNT10 Tbio Enzyme -0.88348 7.68 127