Development Level

Tbio 137 | 11,651
Tchem 24 | 1,388
Tclin 12 | 612
Tdark 9 | 6,593

Collection

GPCR: IDG Consortium (Complete... 2 | 25
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
abnormal embryo size 5 | 220
decreased vertical activity 5 | 208
preweaning lethality, complete... 5 | 979
abnormal lens morphology 4 | 81
cataract 4 | 92
increased lean body mass 4 | 172
abnormal epididymis morphology 3 | 42
decreased lymphocyte cell numb... 3 | 83
enlarged epididymis 3 | 31
abnormal coat-hair pigmentatio... 2 | 64
abnormal facial morphology 2 | 17
abnormal head shape 2 | 10
abnormal heart morphology 2 | 162
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
absent vibrissae 2 | 12
decreased circulating calcium ... 2 | 36
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased red blood cell distr... 2 | 41
decreased threshold for audito... 2 | 26
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral content 2 | 108
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal locomotor activation 1 | 16
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent teeth 1 | 3
anophthalmia 1 | 33
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small kidney 1 | 16
stereotypic behavior 1 | 3
thrombocytosis 1 | 27
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Barrett's esophagus 182 | 182
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 180 | 17,369
Endocrine System 179 | 18,159
Blood and immune system 178 | 16,909
Female tissues 178 | 17,400
Liver and Pancreas 178 | 16,750
Skin and soft tissues 178 | 17,230
Urinary Tract 178 | 16,678
Male tissues 177 | 17,142
Nervous System 175 | 16,725
Respiratory system 174 | 16,393
Cardiovascular System 160 | 15,192

Target Family

Non-IDG 99 | 12,091
Enzyme 48 | 4,145
Transporter 12 | 473
Transcription Factor 9 | 1,400
Kinase 7 | 634
GPCR 3 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DnaJ homolog subfamily C member 22 DNAJC22 Tbio Non-IDG -1.84897 65.6 70
E3 ubiquitin-protein ligase CBL-B CBLB Tbio Enzyme -0.82313 6.58 193
Cathepsin E CTSE Tchem Enzyme -2.33724 227.7 192
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.09168 112.5 175
Cbp/p300-interacting transactivator 2 CITED2 Tbio Non-IDG -2.07760 134.8 167
Protein C-ets-2 ETS2 Tbio Transcription Factor -2.40902 253.3 272
Plasmalemma vesicle-associated protein PLVAP Tbio Non-IDG -2.30946 195.9 167
Protein NDRG2 NDRG2 Tbio Non-IDG -1.94343 142.1 289
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.61683 3311.4 251
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164