Development Level

Tbio 1,064 | 11,445
Tchem 216 | 1,598
Tclin 143 | 613
Tdark 19 | 6,588

Collection

Ion Channel: IDG Consortium (T... 6 | 99
Kinase: IDG Consortium (Comple... 3 | 37
Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 156 | 979
embryonic lethality prior to o... 45 | 239
preweaning lethality, incomple... 45 | 499
embryonic lethality prior to t... 44 | 278
abnormal embryo size 33 | 220
abnormal behavior 32 | 298
enlarged heart 26 | 210
decreased total body fat amoun... 24 | 207
decreased body weight 22 | 161
hypoactivity 22 | 132
decreased bone mineral content 21 | 151
decreased vertical activity 20 | 208
decreased bone mineral density 19 | 126
increased lean body mass 18 | 172
abnormal bone structure 17 | 187
abnormal heart morphology 17 | 162
decreased grip strength 17 | 116
increased circulating alkaline... 17 | 122
increased total body fat amoun... 17 | 134
abnormal seminal vesicle morph... 16 | 114
embryonic growth retardation 16 | 106
cataract 15 | 92
decreased mean corpuscular vol... 15 | 79
hyperactivity 15 | 148
increased bone mineral content 15 | 108
increased mean corpuscular hem... 15 | 96
male infertility 15 | 123
short tibia 15 | 97
small superior vagus ganglion 15 | 74
abnormal lens morphology 14 | 81
decreased startle reflex 14 | 75
decreased lymphocyte cell numb... 13 | 83
impaired glucose tolerance 13 | 75
increased circulating sodium l... 13 | 71
prenatal lethality prior to he... 13 | 87
abnormal gait 12 | 69
decreased circulating glucose ... 12 | 126
improved glucose tolerance 12 | 79
increased or absent threshold ... 12 | 101
abnormal retina morphology 11 | 71
decreased hemoglobin content 11 | 68
decreased lean body mass 11 | 135
enlarged lymph nodes 11 | 37
hydrometra 11 | 53
increased startle reflex 11 | 112
thrombocytopenia 11 | 56
abnormal eye morphology 10 | 68
decreased circulating choleste... 10 | 93
decreased circulating triglyce... 10 | 79
decreased erythrocyte cell num... 10 | 62
decreased fasted circulating g... 10 | 65
decreased neutrophil cell numb... 9 | 42
decreased prepulse inhibition 9 | 82
decreased red blood cell distr... 9 | 41
increased bone mineral density 9 | 72
increased heart weight 9 | 62
small testis 9 | 58
tremors 9 | 39
abnormal neural tube closure 8 | 46
decreased circulating HDL chol... 8 | 68
decreased circulating amylase ... 8 | 28
increased blood urea nitrogen ... 8 | 48
increased circulating chloride... 8 | 41
increased leukocyte cell numbe... 8 | 47
persistence of hyaloid vascula... 8 | 33
prolonged ST segment 8 | 36
decreased blood urea nitrogen ... 7 | 51
decreased body length 7 | 101
decreased heart weight 7 | 27
increased circulating HDL chol... 7 | 80
increased circulating bilirubi... 7 | 16
increased circulating choleste... 7 | 66
increased circulating potassiu... 7 | 29
increased fasted circulating g... 7 | 76
increased lymphocyte cell numb... 7 | 32
increased mean platelet volume 7 | 45
increased monocyte cell number 7 | 63
limb grasping 7 | 41
prolonged QT interval 7 | 38
abnormal coat-hair pigmentatio... 6 | 64
abnormal embryo turning 6 | 31
abnormal retinal vasculature m... 6 | 27
abnormal skin morphology 6 | 50
abnormal sleep behavior 6 | 70
cardiovascular system phenotyp... 6 | 36
decreased circulating alanine ... 6 | 47
decreased circulating serum al... 6 | 82
decreased leukocyte cell numbe... 6 | 73
decreased mean corpuscular hem... 6 | 50
decreased mean platelet volume 6 | 25
edema 6 | 59
enlarged spleen 6 | 41
increased circulating calcium ... 6 | 34
pallor 6 | 34
prenatal lethality 6 | 28
small kidney 6 | 16
abnormal kidney morphology 5 | 65
decreased circulating alkaline... 5 | 46
decreased circulating insulin ... 5 | 76
thrombocytosis 5 | 27

Disease

Autosomal recessive predisposition 1,442 | 1,442
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 1,416 | 18,159
Digestive Tract 1,391 | 17,369
Female tissues 1,377 | 17,400
Skin and soft tissues 1,372 | 17,230
Male tissues 1,366 | 17,142
Liver and Pancreas 1,361 | 16,750
Urinary Tract 1,359 | 16,678
Blood and immune system 1,354 | 16,909
Nervous System 1,342 | 16,725
Respiratory system 1,312 | 16,393
Cardiovascular System 1,227 | 15,192

Target Family

Non-IDG 648 | 12,091
Enzyme 513 | 4,145
Kinase 72 | 634
Transporter 66 | 473
Transcription Factor 64 | 1,400
Ion Channel 40 | 344
GPCR 19 | 408
Nuclear Receptor 10 | 48
Epigenetic 7 | 242
TF/Epigenetic 3 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 Tchem Enzyme -1.80418 63.8 91