Development Level

Tbio 245 | 11,651
Tclin 65 | 612
Tchem 45 | 1,388
Tdark 9 | 6,593

Collection

Ion Channel: IDG Consortium (T... 5 | 99
RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 18 | 979
abnormal behavior 12 | 298
preweaning lethality, incomple... 12 | 499
decreased total body fat amoun... 9 | 207
increased lean body mass 8 | 172
decreased circulating HDL chol... 6 | 68
decreased grip strength 6 | 116
decreased lymphocyte cell numb... 6 | 83
abnormal bone structure 5 | 187
decreased body length 5 | 101
decreased body weight 5 | 161
decreased circulating alanine ... 5 | 47
decreased circulating choleste... 5 | 93
decreased circulating serum al... 5 | 82
decreased lean body mass 5 | 135
embryonic lethality prior to t... 5 | 278
enlarged heart 5 | 210
hyperactivity 5 | 148
hypoactivity 5 | 132
increased total body fat amoun... 5 | 134
abnormal behavioral response t... 4 | 66
abnormal locomotor behavior 4 | 24
abnormal sleep behavior 4 | 70
decreased circulating insulin ... 4 | 76
decreased vertical activity 4 | 208
increased circulating chloride... 4 | 41
increased fasted circulating g... 4 | 76
increased neutrophil cell numb... 4 | 46
microphthalmia 4 | 26
short tibia 4 | 97
abnormal embryo size 3 | 220
abnormal epididymis morphology 3 | 42
abnormal retina morphology 3 | 71
abnormal retinal vasculature m... 3 | 27
abnormal seminal vesicle morph... 3 | 114
decreased blood urea nitrogen ... 3 | 51
decreased circulating alkaline... 3 | 46
decreased circulating creatini... 3 | 39
decreased circulating glucose ... 3 | 126
decreased fasted circulating g... 3 | 65
decreased pulmonary respirator... 3 | 5
decreased startle reflex 3 | 75
embryonic lethality prior to o... 3 | 239
impaired glucose tolerance 3 | 75
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating potassiu... 3 | 29
increased circulating sodium l... 3 | 71
increased erythrocyte cell num... 3 | 39
increased or absent threshold ... 3 | 101
male infertility 3 | 123
thrombocytopenia 3 | 56
tremors 3 | 39
abnormal heart morphology 2 | 162
abnormal iris morphology 2 | 13
abnormal lung morphology 2 | 26
abnormal testis morphology 2 | 43
abnormal vitreous body morphol... 2 | 10
corneal opacity 2 | 32
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased circulating fructosa... 2 | 30
decreased circulating phosphat... 2 | 27
decreased circulating total pr... 2 | 49
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
edema 2 | 59
embryonic growth retardation 2 | 106
enlarged stomach 2 | 2
increased bone mineral content 2 | 108
increased circulating amylase ... 2 | 25
increased circulating triglyce... 2 | 42
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
increased vertical activity 2 | 24
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
small testis 2 | 58
small thymus 2 | 16
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal spleen morphology 1 | 55
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased neutrophil cell numb... 1 | 42
impaired pupillary reflex 1 | 26
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased mean corpuscular vol... 1 | 92

Disease

Autistic Disorder 364 | 364
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 350 | 18,159
Female tissues 340 | 17,400
Digestive Tract 337 | 17,369
Nervous System 337 | 16,725
Skin and soft tissues 337 | 17,230
Male tissues 329 | 17,142
Urinary Tract 325 | 16,678
Blood and immune system 323 | 16,909
Liver and Pancreas 322 | 16,750
Respiratory system 311 | 16,393
Cardiovascular System 282 | 15,192

Target Family

Non-IDG 171 | 12,091
Enzyme 73 | 4,145
Ion Channel 30 | 344
Transcription Factor 28 | 1,400
GPCR 19 | 408
Epigenetic 14 | 242
Transporter 13 | 473
Kinase 12 | 634
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific NSD1 Tbio Epigenetic -2.16239 142.5 123