Development Level

Tbio 198 | 10,625
Tclin 57 | 602
Tchem 55 | 1,890
Tdark 10 | 7,003

Collection

Eligible Ion Channel Proteins 7 | 117
Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, incomple... 11 | 260
abnormal behavior 9 | 226
preweaning lethality, complete... 9 | 633
decreased grip strength 7 | 123
increased lean body mass 7 | 107
decreased lean body mass 6 | 195
decreased total body fat amoun... 5 | 186
hypoactivity 5 | 89
short tibia 5 | 82
decreased body length 4 | 108
decreased body weight 4 | 174
decreased circulating HDL chol... 4 | 77
decreased circulating insulin ... 4 | 75
hyperactivity 4 | 108
abnormal bone structure 3 | 131
abnormal epididymis morphology 3 | 31
abnormal heart left ventricle ... 3 | 20
decreased bone mineral density 3 | 126
decreased circulating alanine ... 3 | 53
decreased circulating choleste... 3 | 85
decreased circulating serum al... 3 | 79
decreased fasted circulating g... 3 | 49
decreased pulmonary respirator... 3 | 4
embryonic lethality prior to t... 3 | 187
enlarged heart 3 | 111
increased circulating alkaline... 3 | 119
increased fasted circulating g... 3 | 68
tremors 3 | 34
abnormal behavioral response t... 2 | 52
abnormal cornea morphology 2 | 24
abnormal locomotor activation 2 | 26
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
abnormal tail movements 2 | 12
corneal opacity 2 | 25
decreased bone mineral content 2 | 157
decreased circulating alkaline... 2 | 41
decreased circulating glucose ... 2 | 121
decreased hemoglobin content 2 | 53
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to o... 2 | 148
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 52
increased blood urea nitrogen ... 2 | 44
increased body weight 2 | 42
increased bone mineral content 2 | 92
increased grip strength 2 | 83
increased mean platelet volume 2 | 19
increased sacral vertebrae num... 2 | 62
lethargy 2 | 5
microphthalmia 2 | 15
prenatal lethality prior to he... 2 | 64
small thymus 2 | 11
straub tail 2 | 26
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal lung morphology 1 | 15
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal urinary bladder morph... 1 | 2
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
convulsive seizures 1 | 11
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased neutrophil cell numb... 1 | 37
decreased thoracic vertebrae n... 1 | 7
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
impaired righting response 1 | 19
increased CD4-positive NK T ce... 1 | 3
increased CD4-positive, CD25-p... 1 | 18
increased NK T cell number 1 | 11
increased body length 1 | 20
increased circulating alanine ... 1 | 11
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased rib number 1 | 41
increased startle reflex 1 | 38
limb grasping 1 | 35
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

Autistic Disorder 320 | 320
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327

Tissue

Female tissues 317 | 18,647
Nervous System 317 | 18,561
Endocrine System 316 | 18,512
Digestive Tract 315 | 18,473
Urinary Tract 313 | 18,444
Blood and immune system 311 | 17,995
Cardiovascular System 310 | 17,958
Liver and Pancreas 310 | 18,136
Male tissues 309 | 17,969
Skin and soft tissues 308 | 18,115
Respiratory system 305 | 17,484

Target Family

Non-IDG 149 | 11,971
Enzyme 67 | 4,146
Ion Channel 26 | 341
Transcription Factor 25 | 1,400
GPCR 18 | 406
Transporter 11 | 473
Epigenetic 10 | 242
Kinase 10 | 634
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Class A basic helix-loop-helix protein 9 BHLHA9 Tbio Transcription Factor -1.04597 11.2 52
Contactin-6 CNTN6 Tbio Non-IDG -2.02527 101.3 65
Inositol polyphosphate 1-phosphatase INPP1 Tbio Enzyme -1.22269 17.2 73
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 KCTD13 Tbio Non-IDG -0.85155 7.65 69
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
Deleted in autism protein 1 C3orf58 Tbio Non-IDG -1.14690 16.5 72