Development Level

Tbio 662 | 11,445
Tchem 127 | 1,598
Tdark 118 | 6,588
Tclin 45 | 613

Collection

Ion Channel: IDG Consortium (T... 5 | 99
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 36 | 979
preweaning lethality, incomple... 29 | 499
decreased total body fat amoun... 19 | 207
decreased vertical activity 19 | 208
abnormal behavior 17 | 298
enlarged heart 14 | 210
abnormal heart morphology 13 | 162
decreased body weight 13 | 161
increased lean body mass 12 | 172
decreased grip strength 11 | 116
embryonic lethality prior to t... 11 | 278
hypoactivity 11 | 132
increased total body fat amoun... 11 | 134
abnormal bone structure 10 | 187
decreased bone mineral content 10 | 151
increased bone mineral content 10 | 108
thrombocytopenia 10 | 56
abnormal embryo size 9 | 220
increased mean corpuscular vol... 9 | 92
abnormal testis morphology 8 | 43
decreased circulating glucose ... 8 | 126
decreased prepulse inhibition 8 | 82
decreased startle reflex 8 | 75
embryonic lethality prior to o... 8 | 239
impaired glucose tolerance 8 | 75
increased fasted circulating g... 8 | 76
increased or absent threshold ... 8 | 101
small testis 8 | 58
abnormal behavioral response t... 7 | 66
abnormal gait 7 | 69
abnormal seminal vesicle morph... 7 | 114
decreased body length 7 | 101
decreased bone mineral density 7 | 126
decreased circulating choleste... 7 | 93
decreased lean body mass 7 | 135
increased circulating alkaline... 7 | 122
increased heart weight 7 | 62
increased hematocrit 7 | 46
abnormal eye morphology 6 | 68
cataract 6 | 92
decreased circulating insulin ... 6 | 76
decreased mean corpuscular vol... 6 | 79
increased blood urea nitrogen ... 6 | 48
increased circulating HDL chol... 6 | 80
increased circulating triglyce... 6 | 42
increased leukocyte cell numbe... 6 | 47
abnormal coat-hair pigmentatio... 5 | 64
abnormal retina morphology 5 | 71
abnormal sleep behavior 5 | 70
decreased circulating HDL chol... 5 | 68
edema 5 | 59
embryonic growth retardation 5 | 106
female infertility 5 | 60
hyperactivity 5 | 148
increased circulating choleste... 5 | 66
increased mean corpuscular hem... 5 | 96
increased neutrophil cell numb... 5 | 46
increased startle reflex 5 | 112
male infertility 5 | 123
short tibia 5 | 97
small superior vagus ganglion 5 | 74
abnormal kidney morphology 4 | 65
abnormal lens morphology 4 | 81
abnormal tail morphology 4 | 25
abnormal tooth morphology 4 | 24
corneal opacity 4 | 32
decreased caudal vertebrae num... 4 | 53
decreased circulating alanine ... 4 | 47
decreased circulating serum al... 4 | 82
decreased heart weight 4 | 27
decreased hemoglobin content 4 | 68
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular hem... 4 | 31
decreased neutrophil cell numb... 4 | 42
improved glucose tolerance 4 | 79
increased bone mineral density 4 | 72
increased circulating bilirubi... 4 | 16
increased circulating chloride... 4 | 41
increased mean platelet volume 4 | 45
increased monocyte cell number 4 | 63
limb grasping 4 | 41
abnormal cornea morphology 3 | 31
abnormal cranium morphology 3 | 36
abnormal locomotor behavior 3 | 24
abnormal retinal vasculature m... 3 | 27
abnormal vibrissa morphology 3 | 25
cardiovascular system phenotyp... 3 | 36
decreased circulating bilirubi... 3 | 19
decreased circulating calcium ... 3 | 36
decreased circulating creatini... 3 | 39
increased circulating amylase ... 3 | 25
increased circulating calcium ... 3 | 34
increased hemoglobin content 3 | 45
pale yolk sac 3 | 25
pallor 3 | 34
prenatal lethality prior to he... 3 | 87
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
tremors 3 | 39

Disease

Atopic dermatitis 952 | 952
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Skin and soft tissues 917 | 17,230
Female tissues 916 | 17,400
Digestive Tract 915 | 17,369
Endocrine System 908 | 18,159
Blood and immune system 902 | 16,909
Urinary Tract 888 | 16,678
Liver and Pancreas 886 | 16,750
Male tissues 885 | 17,142
Respiratory system 873 | 16,393
Nervous System 866 | 16,725
Cardiovascular System 824 | 15,192

Target Family

Non-IDG 584 | 12,091
Enzyme 234 | 4,145
Transcription Factor 44 | 1,400
Kinase 32 | 634
Transporter 20 | 473
GPCR 16 | 408
Ion Channel 10 | 344
Nuclear Receptor 7 | 48
Epigenetic 3 | 242
TF/Epigenetic 1 | 38
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
ADP-ribosylation factor-like protein 5A ARL5A Tbio Enzyme -1.27307 18.8 53
Peptidyl-prolyl cis-trans isomerase FKBP7 FKBP7 Tbio Enzyme -1.41965 24.7 112
LHFPL tetraspan subfamily member 6 protein LHFPL6 Tdark Non-IDG -0.47054 2.66 66
Acidic leucine-rich nuclear phosphoprotein 32 family member E ANP32E Tbio Non-IDG -0.82034 5.60 97
Cholesterol 25-hydroxylase CH25H Tbio Enzyme -1.54426 38.2 54
Connector enhancer of kinase suppressor of ras 2 CNKSR2 Tbio Enzyme -1.11551 14.5 71
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
IgGFc-binding protein FCGBP Tbio Non-IDG -1.31482 19.9 0