Development Level

Tbio 2,076 | 11,445
Tdark 533 | 6,588
Tchem 320 | 1,598
Tclin 152 | 613

Collection

Ion Channel: IDG Consortium (T... 31 | 99
Kinase: IDG Consortium (Target... 22 | 125
GPCR: IDG Consortium (Targets) 9 | 126
Kinase: IDG Consortium (Comple... 9 | 37
GPCR: IDG Consortium (Complete... 7 | 25

IMPC Phenotype

preweaning lethality, incomple... 109 | 499
preweaning lethality, complete... 104 | 979
abnormal behavior 68 | 298
decreased total body fat amoun... 55 | 207
abnormal bone structure 44 | 187
hyperactivity 44 | 148
increased circulating alkaline... 39 | 122
decreased vertical activity 36 | 208
decreased grip strength 34 | 116
increased lean body mass 34 | 172
embryonic lethality prior to t... 33 | 278
increased bone mineral content 32 | 108
decreased body weight 31 | 161
decreased bone mineral content 31 | 151
enlarged heart 30 | 210
hypoactivity 30 | 132
abnormal embryo size 29 | 220
decreased lean body mass 28 | 135
increased total body fat amoun... 24 | 134
decreased bone mineral density 23 | 126
increased startle reflex 23 | 112
cataract 22 | 92
decreased circulating glucose ... 22 | 126
increased mean corpuscular hem... 22 | 96
abnormal sleep behavior 21 | 70
decreased lymphocyte cell numb... 21 | 83
decreased startle reflex 21 | 75
abnormal gait 20 | 69
decreased circulating serum al... 20 | 82
short tibia 20 | 97
decreased body length 19 | 101
embryonic lethality prior to o... 19 | 239
increased circulating HDL chol... 19 | 80
male infertility 19 | 123
abnormal heart morphology 18 | 162
abnormal seminal vesicle morph... 18 | 114
decreased prepulse inhibition 18 | 82
improved glucose tolerance 18 | 79
decreased circulating insulin ... 17 | 76
decreased mean corpuscular vol... 17 | 79
abnormal eye morphology 16 | 68
abnormal lens morphology 16 | 81
decreased circulating triglyce... 16 | 79
decreased hemoglobin content 16 | 68
increased bone mineral density 16 | 72
increased circulating choleste... 16 | 66
increased monocyte cell number 16 | 63
decreased circulating calcium ... 15 | 36
decreased circulating choleste... 15 | 93
decreased erythrocyte cell num... 15 | 62
decreased leukocyte cell numbe... 15 | 73
increased circulating chloride... 15 | 41
decreased fasted circulating g... 14 | 65
increased blood urea nitrogen ... 14 | 48
increased or absent threshold ... 14 | 101
abnormal coat-hair pigmentatio... 13 | 64
abnormal epididymis morphology 13 | 42
abnormal retina morphology 13 | 71
decreased circulating alanine ... 13 | 47
decreased hematocrit 13 | 46
decreased mean corpuscular hem... 13 | 50
increased circulating sodium l... 13 | 71
increased fasted circulating g... 13 | 76
increased mean corpuscular vol... 13 | 92
limb grasping 13 | 41
abnormal behavioral response t... 12 | 66
abnormal kidney morphology 12 | 65
abnormal skin morphology 12 | 50
decreased circulating HDL chol... 12 | 68
increased heart weight 12 | 62
decreased circulating LDL chol... 11 | 38
decreased circulating amylase ... 11 | 28
enlarged lymph nodes 11 | 37
impaired righting response 11 | 26
increased circulating calcium ... 11 | 34
increased erythrocyte cell num... 11 | 39
increased mean corpuscular hem... 11 | 36
increased neutrophil cell numb... 11 | 46
prenatal lethality prior to he... 11 | 87
small testis 11 | 58
thrombocytopenia 11 | 56
tremors 11 | 39
abnormal testis morphology 10 | 43
decreased blood urea nitrogen ... 10 | 51
decreased circulating alkaline... 10 | 46
female infertility 10 | 60
increased circulating potassiu... 10 | 29
increased hematocrit 10 | 46
increased leukocyte cell numbe... 10 | 47
increased mean platelet volume 10 | 45
increased red blood cell distr... 10 | 34
small superior vagus ganglion 10 | 74
abnormal locomotor behavior 9 | 24
cardiovascular system phenotyp... 9 | 36
decreased mean corpuscular hem... 9 | 31
embryonic growth retardation 9 | 106
enlarged epididymis 9 | 31
impaired glucose tolerance 9 | 75
increased circulating triglyce... 9 | 42
increased vertical activity 9 | 24

Disease

Astrocytoma, Pilocytic 3,081 | 3,081
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Nervous System 3,053 | 16,725
Endocrine System 3,049 | 18,159
Digestive Tract 3,006 | 17,369
Female tissues 3,004 | 17,400
Skin and soft tissues 2,997 | 17,230
Male tissues 2,984 | 17,142
Liver and Pancreas 2,943 | 16,750
Urinary Tract 2,935 | 16,678
Blood and immune system 2,928 | 16,909
Respiratory system 2,890 | 16,393
Cardiovascular System 2,737 | 15,192

Target Family

Non-IDG 1,834 | 12,091
Enzyme 661 | 4,145
Transcription Factor 163 | 1,400
Kinase 130 | 634
Ion Channel 100 | 344
Transporter 82 | 473
GPCR 69 | 408
Epigenetic 24 | 242
TF/Epigenetic 9 | 38
Nuclear Receptor 8 | 48
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoic acid receptor responder protein 3 RARRES3 Tbio Non-IDG -1.84020 71.0 164
Paraneoplastic antigen Ma3 PNMA3 Tbio Non-IDG -1.88721 71.6 105
Zinc finger protein Helios IKZF2 Tbio Transcription Factor -1.26324 15.8 221
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
Heme-binding protein 2 HEBP2 Tbio Non-IDG -1.05941 10.8 114
Disintegrin and metalloproteinase domain-containing protein 28 ADAM28 Tbio Enzyme -1.87527 79.6 110
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
IQ and AAA domain-containing protein 1 IQCA1 Tbio Non-IDG -0.80618 5.26 77