Development Level

Tbio 214 | 11,651
Tchem 94 | 1,388
Tclin 63 | 612
Tdark 14 | 6,593

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 15 | 499
enlarged heart 10 | 210
preweaning lethality, complete... 10 | 979
decreased vertical activity 8 | 208
embryonic lethality prior to t... 8 | 278
abnormal heart morphology 7 | 162
abnormal seminal vesicle morph... 7 | 114
increased monocyte cell number 7 | 63
increased neutrophil cell numb... 7 | 46
decreased lymphocyte cell numb... 6 | 83
decreased total body fat amoun... 6 | 207
embryonic lethality prior to o... 5 | 239
abnormal behavioral response t... 4 | 66
abnormal bone structure 4 | 187
abnormal kidney morphology 4 | 65
improved glucose tolerance 4 | 79
small superior vagus ganglion 4 | 74
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased basophil cell number 3 | 16
decreased mean corpuscular vol... 3 | 79
female infertility 3 | 60
hydrometra 3 | 53
increased bone mineral content 3 | 108
increased lymphocyte cell numb... 3 | 32
increased mean platelet volume 3 | 45
increased total body fat amoun... 3 | 134
male infertility 3 | 123
prolonged ST segment 3 | 36
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal lens morphology 2 | 81
abnormal lung morphology 2 | 26
abnormal spleen morphology 2 | 55
abnormal vibrissa morphology 2 | 25
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased circulating creatini... 2 | 39
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
hyperactivity 2 | 148
impaired righting response 2 | 26
increased circulating magnesiu... 2 | 10
increased hematocrit 2 | 46
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
prolonged QT interval 2 | 38
short tibia 2 | 97
small spleen 2 | 19
thrombocytopenia 2 | 56
abnormal coat- hair morphology 1 | 19
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
convulsive seizures 1 | 13
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased vertical activity 1 | 24
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
small thymus 1 | 16
tremors 1 | 39

Disease

Asthma 385 | 385
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 372 | 17,369
Endocrine System 371 | 18,159
Skin and soft tissues 368 | 17,230
Blood and immune system 367 | 16,909
Female tissues 364 | 17,400
Liver and Pancreas 361 | 16,750
Urinary Tract 360 | 16,678
Male tissues 359 | 17,142
Respiratory system 352 | 16,393
Nervous System 345 | 16,725
Cardiovascular System 322 | 15,192

Target Family

Non-IDG 220 | 12,091
Enzyme 81 | 4,145
GPCR 35 | 408
Transcription Factor 20 | 1,400
Kinase 14 | 634
Ion Channel 5 | 344
Transporter 5 | 473
Nuclear Receptor 3 | 48
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Filaggrin FLG Tbio Non-IDG -3.03594 1055.2 253
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Tumor necrosis factor receptor superfamily member 4 TNFRSF4 Tbio Non-IDG -2.60147 430.2 524
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A Tclin Enzyme -2.09039 125.7 168