Development Level

Tbio 39 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal joint morphology 1 | 23
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal testis morphology 1 | 43
brachydactyly 1 | 19
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased prepulse inhibition 1 | 32
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
syndactyly 1 | 23

Disease

Asphyxiating thoracic dystrophy 44 | 44
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678

Target Family

Non-IDG 32 | 12,091
Enzyme 9 | 4,145
Kinase 2 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase Nek1 NEK1 Tchem Kinase -1.62443 47.0 85
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Centrosomal protein of 120 kDa CEP120 Tbio Non-IDG -0.93215 7.32 49
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23
Intraflagellar transport protein 140 homolog IFT140 Tbio Non-IDG -1.42568 23.3 45
Protein TALPID3 KIAA0586 Tbio Non-IDG -1.37246 24.8 7
Tripartite motif-containing protein 59 TRIM59 Tbio Non-IDG -0.95825 14.1 122
Sulfate transporter SLC26A2 Tbio Transporter -2.46180 284.1 76
Putative phosphatidylinositol 4-kinase alpha-like protein P2 PI4KAP2 Tdark Enzyme -1.08718 27.9 0
WD repeat-containing protein 35 WDR35 Tbio Non-IDG -1.31497 20.6 39