Development Level

Tbio 88 | 11,445
Tchem 19 | 1,598
Tdark 14 | 6,588
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased total body fat amoun... 5 | 207
improved glucose tolerance 4 | 79
preweaning lethality, complete... 4 | 979
abnormal heart morphology 3 | 162
decreased body length 3 | 101
decreased vertical activity 3 | 208
enlarged heart 3 | 210
increased bone mineral content 3 | 108
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal testis morphology 2 | 43
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased mean corpuscular hem... 2 | 31
decreased red blood cell distr... 2 | 41
embryonic growth retardation 2 | 106
hydrometra 2 | 53
increased body length 2 | 32
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
small superior vagus ganglion 2 | 74
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
absent seminal vesicle 1 | 4
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged uterus 1 | 11
female infertility 1 | 60
hemorrhage 1 | 23
increased aggression 1 | 4
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
mydriasis 1 | 6
small uterus 1 | 3
vertebral transformation 1 | 12

Disease

Arthritis, Juvenile 126 | 126
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 125 | 16,909
Endocrine System 124 | 18,159
Male tissues 124 | 17,142
Digestive Tract 123 | 17,369
Female tissues 123 | 17,400
Liver and Pancreas 123 | 16,750
Respiratory system 123 | 16,393
Skin and soft tissues 123 | 17,230
Urinary Tract 123 | 16,678
Cardiovascular System 120 | 15,192
Nervous System 120 | 16,725

Target Family

Non-IDG 69 | 12,091
Enzyme 23 | 4,145
Transcription Factor 17 | 1,400
Kinase 7 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Nuclear Receptor 2 | 48
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA dC->dU-editing enzyme APOBEC-3A APOBEC3A Tbio Non-IDG -1.79111 52.4 187
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
Choline-phosphate cytidylyltransferase B PCYT1B Tbio Enzyme -1.46937 28.8 40
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Prostatic acid phosphatase ACPP Tchem Enzyme -2.37625 249.3 525
R3H domain-containing protein 2 R3HDM2 Tdark Non-IDG -0.82119 4.93 39
Small membrane A-kinase anchor protein C2orf88 Tdark Enzyme -0.35954 2.19 28