Development Level

Tbio 57 | 11,651
Tchem 19 | 1,388
Tclin 14 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal bone structure 3 | 187
decreased body weight 3 | 161
embryonic lethality prior to t... 3 | 278
hydrometra 3 | 53
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
abnormal femur morphology 2 | 14
abnormal joint morphology 2 | 23
abnormal radius morphology 2 | 8
abnormal tibia morphology 2 | 14
abnormal ulna morphology 2 | 8
abnormal vertebrae morphology 2 | 18
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating triglyce... 2 | 79
decreased heart weight 2 | 27
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating potassiu... 2 | 29
increased eosinophil cell numb... 2 | 11
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal cecum morphology 1 | 7
abnormal colon morphology 1 | 3
abnormal digit morphology 1 | 10
abnormal duodenum morphology 1 | 4
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal vertebral arch morpho... 1 | 9
aorta dilation 1 | 3
decreased IgG3 level 1 | 1
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased basophil cell number 1 | 7
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
long tail 1 | 1
long tibia 1 | 25
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
shortened QT interval 1 | 4
small epididymis 1 | 3
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thick tail 1 | 1
vertebral fusion 1 | 23

Disease

Arthralgia 90 | 90
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 88 | 17,369
Female tissues 88 | 17,400
Skin and soft tissues 88 | 17,230
Blood and immune system 87 | 16,909
Endocrine System 87 | 18,159
Liver and Pancreas 87 | 16,750
Male tissues 87 | 17,142
Nervous System 87 | 16,725
Urinary Tract 86 | 16,678
Respiratory system 85 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 25 | 4,145
Transcription Factor 6 | 1,400
Kinase 5 | 634
GPCR 3 | 408
Transporter 3 | 473
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.61157 386.3 882
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Thrombopoietin receptor MPL Tclin Non-IDG -2.74303 582.0 186
Acid ceramidase ASAH1 Tchem Enzyme -2.94716 848.0 203
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Interleukin-2 receptor subunit beta IL2RB Tclin Non-IDG -2.17998 125.4 654
Myeloblastin PRTN3 Tchem Enzyme -3.46597 2968.8 397
Macrophage migration inhibitory factor MIF Tchem Non-IDG -3.21333 1538.5 527
Triggering receptor expressed on myeloid cells 2 TREM2 Tbio Non-IDG -2.42594 269.9 370
Trafficking protein particle complex subunit 2B TRAPPC2 Tbio Non-IDG -1.34114 25.3 6