Targets

Target Filters...

This is where graphics are reside..

Name	Gene	Development Level	Target Family	Log Novelty	Pubmed Score	Antibody Count
Gamma-aminobutyric acid receptor subunit beta-3	GABRB3	Tclin	Ion Channel	-2.11058	130.5	161
Gamma-aminobutyric acid receptor subunit gamma-3	GABRG3	Tclin	Ion Channel	-0.94372	8.18	81
Gamma-aminobutyric acid receptor subunit alpha-4	GABRA4	Tclin	Ion Channel	-1.23307	16.0	235
Adenosine receptor A3	ADORA3	Tchem	GPCR	-2.38749	248.2	42
Gamma-aminobutyric acid receptor subunit alpha-1	GABRA1	Tclin	Ion Channel	-1.77552	55.7	254
Emopamil-binding protein-like	EBPL	Tchem	Non-IDG	-0.65091	3.89	49
Gamma-aminobutyric acid receptor subunit theta	GABRQ	Tclin	Ion Channel	-0.79761	6.15	51
D(2) dopamine receptor	DRD2	Tclin	GPCR	-3.26127	1775.2	248
Gamma-aminobutyric acid receptor subunit alpha-3	GABRA3	Tclin	Ion Channel	-1.50686	31.0	122
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	EBP	Tchem	Enzyme	-2.00134	97.1	114

	abnormal gait	1 \| 51
	impaired glucose tolerance	1 \| 52
	preweaning lethality, incomple...	1 \| 260

	Anxiety	24 \| 24
	ovarian cancer	8,492 \| 8,492
	osteosarcoma	7,933 \| 7,933
	psoriasis	6,685 \| 6,685
	medulloblastoma, large-cell	6,234 \| 6,234
	glioblastoma	5,572 \| 5,572
	lung cancer	4,473 \| 4,473
	atypical teratoid / rhabdoid tumor	4,369 \| 4,369
	intraductal papillary-mucinous neoplasm (IPMN)	3,289 \| 3,289
	malignant mesothelioma	3,163 \| 3,163
	Breast cancer	3,099 \| 3,099
	pilocytic astrocytoma	3,086 \| 3,086
	primitive neuroectodermal tumor	3,031 \| 3,031
	intraductal papillary-mucinous carcinoma (IPMC)	2,988 \| 2,988
	intraductal papillary-mucinous adenoma (IPMA)	2,956 \| 2,956
	invasive ductal carcinoma	2,950 \| 2,950
	oligodendroglioma	2,849 \| 2,849
	lung carcinoma	2,844 \| 2,844
	non-small cell lung cancer	2,798 \| 2,798
	lung adenocarcinoma	2,714 \| 2,714
	pediatric high grade glioma	2,712 \| 2,712
	ependymoma	2,514 \| 2,514
	Cancer	2,346 \| 2,346
	pancreatic cancer	2,300 \| 2,300
	interstitial cystitis	2,299 \| 2,299
	subependymal giant cell astrocytoma	2,287 \| 2,287
	group 3 medulloblastoma	2,254 \| 2,254
	astrocytic glioma	2,241 \| 2,241
	adult high grade glioma	2,148 \| 2,148
	Carcinoma	2,147 \| 2,147
	ulcerative colitis	2,087 \| 2,087
	pituitary cancer	1,972 \| 1,972
	Pick disease	1,893 \| 1,893
	group 4 medulloblastoma	1,875 \| 1,875
	pancreatic ductal adenocarcinoma liver metastasis	1,795 \| 1,795
	ductal carcinoma in situ	1,745 \| 1,745
	cystic fibrosis	1,670 \| 1,670
	diabetes mellitus	1,663 \| 1,663
	breast carcinoma	1,614 \| 1,614
	tuberculosis	1,563 \| 1,563
	posterior fossa group B ependymoma	1,530 \| 1,530
	medulloblastoma	1,524 \| 1,524
	posterior fossa group A ependymoma	1,511 \| 1,511
	astrocytoma	1,493 \| 1,493
	sonic hedgehog group medulloblastoma	1,482 \| 1,482
	colon cancer	1,475 \| 1,475
	adrenocortical carcinoma	1,427 \| 1,427
	Multiple myeloma	1,328 \| 1,328
	primary pancreatic ductal adenocarcinoma	1,271 \| 1,271
	juvenile dermatomyositis	1,189 \| 1,189
	Rheumatoid Arthritis	1,171 \| 1,171
	acute quadriplegic myopathy	1,157 \| 1,157
	atypical teratoid/rhabdoid tumor	1,095 \| 1,095
	spina bifida	1,064 \| 1,064
	cutaneous lupus erythematosus	1,056 \| 1,056
	nasopharyngeal carcinoma	1,056 \| 1,056
	dermatomyositis	967 \| 967
	Atopic dermatitis	944 \| 944
	active Crohn's disease	918 \| 918
	non primary Sjogren syndrome sicca	840 \| 840
	gastric carcinoma	832 \| 832
	primary Sjogren syndrome	789 \| 789
	acute myeloid leukemia	785 \| 785
	Waldenstrons macroglobulinemia	765 \| 765
	esophageal adenocarcinoma	737 \| 737
	tuberculosis and treatment for 6 months	686 \| 686
	progressive supranuclear palsy	674 \| 674
	aldosterone-producing adenoma	664 \| 664
	Alzheimer's disease	644 \| 644
	Obesity	616 \| 616
	Duchenne muscular dystrophy	602 \| 602
	Intellectual disability	573 \| 573
	pancreatic carcinoma	567 \| 567
	fibroadenoma	557 \| 557
	hepatocellular carcinoma	550 \| 550
	Down syndrome	548 \| 548
	Endometriosis	535 \| 535
	chronic rhinosinusitis	512 \| 512
	Schizophrenia	503 \| 503
	autosomal dominant Emery-Dreifuss muscular dystrophy	499 \| 499
	Multiple Sclerosis	498 \| 498
	mucosa-associated lymphoid tissue lymphoma	480 \| 480
	active ulcerative colitis	477 \| 477
	Prostatic Neoplasms	471 \| 471
	IGA Glomerulonephritis	454 \| 454
	gastric cancer	436 \| 436
	Amyotrophic Lateral Sclerosis	432 \| 432
	non-small cell lung carcinoma	413 \| 413
	Mammary Neoplasms	410 \| 410
	inflammatory breast cancer	404 \| 404
	Kidney disease	397 \| 397
	Neurodegenerative disease	383 \| 383
	sarcoidosis	368 \| 368
	Parkinson's disease	364 \| 364
	Asthma	349 \| 349
	glioblastoma multiforme	347 \| 347
	Epilepsy	346 \| 346
	Polycystic Ovary Syndrome	335 \| 335
	nephrosclerosis	329 \| 329
	tuberculosis and treatment for 3 months	327 \| 327
	Autistic Disorder	320 \| 320

	Female tissues	23 \| 18,647
	Male tissues	23 \| 17,969
	Blood and immune system	22 \| 17,995
	Cardiovascular System	22 \| 17,958
	Digestive Tract	22 \| 18,473
	Endocrine System	22 \| 18,512
	Nervous System	22 \| 18,561
	Skin and soft tissues	22 \| 18,115
	Urinary Tract	22 \| 18,444
	Liver and Pancreas	21 \| 18,136
	Respiratory system	20 \| 17,484

	Ion Channel	16 \| 341
	GPCR	5 \| 408
	Enzyme	1 \| 4,146
	Non-IDG	1 \| 11,969
	Transporter	1 \| 473

Development Level

Collection

IMPC Term

Disease

Tissue

Target Family

Drug Target Ontology

Target Development Level

Target Family

PANTHER Protein Ontology

Ligand

GTEx Tissue

HPA RNA Tissue

HPA Protein Tissue

HPM Tissue

JAX/MGI Phenotype

OMIM Phenotype

GWAS Trait

GO Component

UniProt Keywords

Grant Funding IC

Grant Activity

Data Source