Development Level

Tbio 177 | 10,625
Tchem 39 | 1,890
Tclin 33 | 602
Tdark 3 | 7,003

IMPC Term

preweaning lethality, complete... 7 | 633
preweaning lethality, incomple... 6 | 260
embryonic lethality prior to t... 4 | 187
increased mean corpuscular hem... 4 | 93
abnormal cornea morphology 3 | 24
corneal opacity 3 | 25
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased circulating glucose ... 3 | 121
decreased circulating insulin ... 3 | 75
decreased circulating triglyce... 3 | 83
decreased hemoglobin content 3 | 53
decreased mean corpuscular hem... 3 | 34
decreased mean corpuscular vol... 3 | 50
decreased total body fat amoun... 3 | 186
embryonic lethality prior to o... 3 | 148
abnormal bone structure 2 | 131
abnormal cranium morphology 2 | 32
abnormal epididymis morphology 2 | 31
abnormal retinal pigmentation 2 | 61
abnormal skin morphology 2 | 23
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 19
decreased monocyte cell number 2 | 28
increased circulating alkaline... 2 | 119
increased circulating iron lev... 2 | 25
increased hematocrit 2 | 36
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 25
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
narrow eye opening 2 | 15
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal lumbar vertebrae morp... 1 | 6
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal whole-body plethysmog... 1 | 4
anophthalmia 1 | 20
decreased Ly6C high monocyte n... 1 | 18
decreased T-helper cell number 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating calcium ... 1 | 33
decreased circulating iron lev... 1 | 25
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased total retina thickne... 1 | 20
enlarged spleen 1 | 26
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased blood uric acid leve... 1 | 5
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean platelet volume 1 | 19
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
long tibia 1 | 13
prolonged PR interval 1 | 4
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Anemia 252 | 252
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 232 | 18,473
Urinary Tract 232 | 18,444
Nervous System 231 | 18,561
Blood and immune system 230 | 17,995
Liver and Pancreas 230 | 18,136
Endocrine System 229 | 18,512
Female tissues 229 | 18,647
Skin and soft tissues 225 | 18,115
Cardiovascular System 223 | 17,958
Respiratory system 221 | 17,484
Male tissues 220 | 17,969

Target Family

Non-IDG 157 | 11,971
Enzyme 64 | 4,146
Transporter 11 | 473
Transcription Factor 10 | 1,400
Kinase 5 | 634
Ion Channel 4 | 341
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -1.99222 118.1 102
Erythroid transcription factor GATA1 Tbio Transcription Factor -2.97791 941.1 675
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Glycophorin-A GYPA Tbio Non-IDG -3.07931 1160.8 704
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167